Application | Comment | Organism |
---|---|---|
medicine | CPG2 possesses several properties that make it suitable for suicide gene therapy | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00171 | - |
[4-[bis(2-chloroethyl)amino]-3,5-difluorobenzoyl]-L-glutamic acid | - |
Homo sapiens | |
0.0035 | - |
[4-[bis(2-hydroxyethyl)amino]-3,5-difluorobenzoyl]-L-glutamic acid | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
human cancer cell lines are targeted by a vector carrying the CPG2 gene, CPG2 gene originates from different organism | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
MDA-MB-361 cell | target cell for gene therapy | Homo sapiens | - |
WiDr cell | target cell for gene therapy | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
[4-[bis(2-chloroethyl)amino]-3,5-difluorobenzoyl]-L-glutamic acid + H2O | prodrug activated by CPG2 | Homo sapiens | ? | - |
? | |
[4-[bis(2-hydroxyethyl)amino]-3,5-difluorobenzoyl]-L-glutamic acid + H2O | prodrug activated by CPG2 | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
carboxypeptidase G2 | - |
Homo sapiens |
CPG2 | - |
Homo sapiens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
732 | - |
[4-[bis(2-chloroethyl)amino]-3,5-difluorobenzoyl]-L-glutamic acid | - |
Homo sapiens | |
747 | - |
[4-[bis(2-hydroxyethyl)amino]-3,5-difluorobenzoyl]-L-glutamic acid | - |
Homo sapiens |