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Literature summary for 3.4.17.10 extracted from
- Carboxypeptidase H. A regulatory peptide-processing enzyme produced by human hepatoma Hep G2 cells (1989), J. Biol. Chem., 264, 15662-15667.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| EDTA | - |
Homo sapiens |  |
| Guanidinoethylmercaptosuccinic acid | - |
Homo sapiens | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Co2+ | activates | Homo sapiens | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 52000 | 54000 | gel filtration | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| side-chain modification | glycoprotein | Homo sapiens |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| culture medium | contitioned culture medium, from hepatoma cells | Homo sapiens | - |
Storage Stability
| Storage Stability | Organism |
|---|---|
| 4°C, partially purified enzyme, 1 month, 90% loss of activity | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| furylacrylic-Ala-Arg + H2O | - |
Homo sapiens | furylacrylic-Ala + Arg | - |
? | |
| [Leu5]enkephalin-Arg6-Arg7 + H2O | - |
Homo sapiens | [Leu5]enkephalin + Arg | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 5.5 | - |
- |
Homo sapiens |
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Release 2023.1 (January 2023)
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