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Literature summary for 3.4.17.10 extracted from

  • Qin, X.Y.; Cheng, Y.; Murthy, S.R.; Selvaraj, P.; Loh, Y.P.
    carboxypeptidase E-DELTAN, a neuroprotein transiently expressed during development protects embryonic neurons against glutamate neurotoxicity (2014), PLoS ONE, 9, e112996.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Mus musculus
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Source Tissue

Source Tissue Comment Organism Textmining
embryo transiently expressed in mouse embryos from embryonic day 5.5 to postnatal day 1 Mus musculus
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hippocampus CPE-DELTAN expression is up-regulated in embryonic hippocampal neurons in response to dexamethasone treatment Mus musculus
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Synonyms

Synonyms Comment Organism
carboxypeptidase E-DELTAN
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Mus musculus
CPE-DELTAN
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Mus musculus

Expression

Organism Comment Expression
Mus musculus CPE-DELTAN expression is up-regulated in embryonic hippocampal neurons in response to dexamethasone treatment up

General Information

General Information Comment Organism
physiological function CPE-DELTA neuroprotects neurons against glutamate neuroexcitotoxicity and H2O2-induced oxidative stress.CPE-DELTAN acts by increasing the transcription and secretion of fibroblast growth factor (FGF2) Mus musculus