Literature summary for 3.4.16.6 extracted from

Sidyelyeva, G.; Baker, N.E.; Fricker, L.D.
Characterization of the molecular basis of the Drosophila mutations in carboxypeptidase D. Effect on enzyme activity and expression (2006), J. Biol. Chem., 281, 13844-13852.

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Protein Variants

Protein Variants	Comment	Organism
additional information	enzyme is encoded by silver gene svr. Mutant lines svrPG33 do not survive past the early larval stage, having a P-element insertion upstream of the initiation ATG. Mutant lines svr1 and svrpoi are viable, with silvery body color and poited wings. svr1 gene has a three-nucleotide deletion in exon 6, svrpoi has a 1072-bp duplication of the gene that introduces a stop codon into the open reading frame. Both mutations eliminate enzyme activity of the second carboxypeptidase-like domain, which reduces levels of the long forms of enzyme but does not affect the levels of the short forms	Drosophila melanogaster

Organism

Organism	UniProt	Comment	Textmining
Drosophila melanogaster	-	enzyme encoded by silver gene svr	-

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Release 2023.1 (January 2023)