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Literature summary for 3.4.16.5 extracted from

  • Reich, M.; Spindler, K.D.; Burret, M.; Kalbacher, H.; Boehm, B.O.; Burster, T.
    Cathepsin A is expressed in primary human antigen-presenting cells (2010), Immunol. Lett., 128, 143-147.
    View publication on PubMed
Search for more literature for 3.4.16.5

Inhibitors

Inhibitors Comment Organism Structure
lactacystin CatA is inhibited by 0.03 mM lactacystin Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosome
-
 Homo sapiens 5764
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
32000
-
 mature form, SDS-PAGE Homo sapiens
50000
-
 proform, SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
B-lymphoblastoid cell
-
 Homo sapiens
-
B-lymphocyte
-
 Homo sapiens
-
culture condition:antigen-presenting cell
-
 Homo sapiens
-
myeloid dendritic cell
-
 Homo sapiens
-
plasmacytoid dendritic cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
FVNQHLCGSHLV + H2O
-
 Homo sapiens FVNQHLCGSH + L-Leu-L-Val + L-Val
-
 ?
FVNQHLCGSHLVEAL + H2O
-
 Homo sapiens FVNQHLCGSHLVE + L-Ala-L-Leu + L-Leu
-
 ?
additional information does not cleave the MBPMu4 peptide VVHPFPPIVTPPPP Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
CatA
-
 Homo sapiens
cathepsin A
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function cathepsin A is involved in the C-terminal fine-tuning of antigenic T cell epitopes in human antigen-presenting cells Homo sapiens