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Literature summary for 3.4.16.5 extracted from

  • Jackman, H.L.; Morris, P.W.; Deddish, P.A.; Skidgel, R.A.; Erd÷s, E.G.
    Inactivation of endothelin I by deamidase (lysosomal protective protein) (1992), J. Biol. Chem., 267, 2872-2875.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
benzyloxycarbonyl-Gly-Leu-Phe-CH2Cl
-
Homo sapiens
diisopropyl fluorophosphate
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
platelet
-
Homo sapiens
-
smooth muscle vascular Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5-dimethylaminonaphthalene-1-sulfonyl-Phe-Leu-Arg + H2O
-
Homo sapiens 5-dimethylaminonaphthalene-1-sulfonyl-Phe-Leu + Arg
-
?
endothelin I + H2O containing the hydrophobic sequence Ile19-Ile20-Trp21-OH Homo sapiens endothelin(1-20) + Trp
-
?

pH Stability

pH Stability pH Stability Maximum Comment Organism
5.5
-
somewhat unstable above at 37°C Homo sapiens