Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-chloromercuribenzoate | complete inhibition at 1 mM | Priestia megaterium | |
benzylpenicillin | 80% inhibition at 0.1 mg/ml | Priestia megaterium | |
cefmetazole | - |
Priestia megaterium | |
Methicillin | - |
Priestia megaterium | |
nocardicin A | - |
Priestia megaterium | |
penicillin | the enzyme is sensitive to inhibition, penicillin-binding profile during development of spores, overview | Priestia megaterium |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Priestia megaterium |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-MurNAc-L-Ala-D-Glu-L-Lys-D-Ala-D-Ala + H2O | Priestia megaterium | i.e. UDP-N-acetylmuraminoyl-pentapeptide, release of D-alanine from UDPMurNAc-pentapeptide substrate | D-Ala + UDP-MurNAc-L-Ala-D-Glu-L-Lys-D-Ala | - |
? | |
UDP-MurNAc-L-Ala-D-Glu-L-Lys-D-Ala-D-Ala + H2O | Priestia megaterium KM / ATCC 13632 | i.e. UDP-N-acetylmuraminoyl-pentapeptide, release of D-alanine from UDPMurNAc-pentapeptide substrate | D-Ala + UDP-MurNAc-L-Ala-D-Glu-L-Lys-D-Ala | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Priestia megaterium | - |
two isozymes penicillin-binding protein 5 and penicillin-binding protein 5a | - |
Priestia megaterium KM / ATCC 13632 | - |
two isozymes penicillin-binding protein 5 and penicillin-binding protein 5a | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | during endospore development in Bacillus megaterium strain KM, unique sporulation-specific penicillin-binding proteins are synthesized and inserted into the forespore membranes, vegetative and stage-V forespore membrane DD-carboxypeptidase, penicillin-binding profile, overview | Priestia megaterium | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-MurNAc-L-Ala-D-Glu-L-Lys-D-Ala-D-Ala + H2O | i.e. UDP-N-acetylmuraminoyl-pentapeptide, release of D-alanine from UDPMurNAc-pentapeptide substrate | Priestia megaterium | D-Ala + UDP-MurNAc-L-Ala-D-Glu-L-Lys-D-Ala | - |
? | |
UDP-MurNAc-L-Ala-D-Glu-L-Lys-D-Ala-D-Ala + H2O | i.e. UDP-N-acetylmuraminoyl-pentapeptide, release of D-alanine from UDPMurNAc-pentapeptide substrate | Priestia megaterium KM / ATCC 13632 | D-Ala + UDP-MurNAc-L-Ala-D-Glu-L-Lys-D-Ala | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | enzyme peptide mapping | Priestia megaterium |
Synonyms | Comment | Organism |
---|---|---|
DD-Carboxypeptidase | - |
Priestia megaterium |
penicillin-binding protein 5 | - |
Priestia megaterium |
penicillin-binding protein 5a | - |
Priestia megaterium |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Priestia megaterium |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5.4 | - |
vegetative and stage-V forespore membrane DD-carboxypeptidase | Priestia megaterium |