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Literature summary for 3.4.15.1 extracted from

  • Mojallal-Tabatabei, Z.; Asoodeh, A.; Housaindokht, M.; Chamani, J.
    Purification and biochemical characterization of angiotensin I-converting enzyme (ACE) from ostrich lung: The effect of 2,2,2-trifluoroethanol on ACE conformation and activity (2013), Process Biochem., 48, 1091-1098.
No PubMed abstract available
Search for more literature for 3.4.15.1

Activating Compound

Activating Compound Comment Organism Structure
cetyltrimethylammonium bromide 0.1 and 1 mM Struthio camelus
SDS 0.1 mM and 10 mM Struthio camelus
Triton X-100 0.01% Struthio camelus

Inhibitors

Inhibitors Comment Organism Structure
captopril
-
 Struthio camelus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.08
-
 2-furanacryloyl-Phe-Gly-Gly pH 7.5, 20°C Struthio camelus

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ activates enzymatic activity Struthio camelus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
200000
-
 SDS-PAGE Struthio camelus

Organism

Organism UniProt Comment Textmining
Struthio camelus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
lung
-
 Struthio camelus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-furanacryloyl-Phe-Gly-Gly + H2O
-
 Struthio camelus 2-furanacryloyl-Phe + Gly-Gly
-
 ?

Synonyms

Synonyms Comment Organism
ACE
-
 Struthio camelus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
20
-
-
 Struthio camelus

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
20 55
-
 Struthio camelus

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
55
-
 90% activity for 30 min Struthio camelus
60
-
 complete inactivation Struthio camelus

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
987
-
 2-furanacryloyl-Phe-Gly-Gly pH 7.5, 20°C Struthio camelus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
-
 Struthio camelus

pH Range

pH Minimum pH Maximum Comment Organism
7.5 8
-
 Struthio camelus

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0000165
-
 captopril pH 7.5, 20°C Struthio camelus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0000365
-
 pH 7.5, 20°C Struthio camelus captopril