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Literature summary for 3.4.15.1 extracted from
- Angiotensin I-converting enzyme (ACE) inhibitory activity and ACE inhibitory peptides of salmon (Salmo salar) protein hydrolysates obtained by human and porcine gastrointestinal enzymes (2014), Int. J. Mol. Sci., 15, 14077-14101.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Ala-Leu-Pro-His-Ala | - |
Homo sapiens |  |
| Ile-Trp | - |
Homo sapiens | |
| Ile-Trp-His-His-Thr | - |
Homo sapiens | |
| Ile-Tyr | - |
Homo sapiens | |
| Ile-Val-Tyr | - |
Homo sapiens | |
| Thr-Val-Tyr | - |
Homo sapiens | |
| Tyr-Ala-Leu-Pro-His-Ala | - |
Homo sapiens | |
| Val-Phe-Pro-Ser | - |
Homo sapiens | |
| Val-Thr-Val-Asn-Pro-Tyr-Lys-Trp-Leu-Pro | - |
Homo sapiens | |
| Val-Trp | - |
Homo sapiens | |
| Val-Tyr | - |
Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| hippuryl-L-His-L-Leu + H2O | - |
Homo sapiens | hippuric acid + L-His-L-Leu | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ACE | - |
Homo sapiens |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.2 | - |
assay at | Homo sapiens |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.00046 | - |
pH 8.2, 37°C | Homo sapiens | Val-Phe-Pro-Ser | |
| 0.00048 | - |
pH 8.2, 37°C | Homo sapiens | Ile-Val-Tyr | |
| 0.0014 | - |
pH 8.2, 37°C | Homo sapiens | Val-Trp | |
| 0.0021 | - |
pH 8.2, 37°C | Homo sapiens | Ile-Tyr | |
| 0.0047 | - |
pH 8.2, 37°C | Homo sapiens | Ile-Trp | |
| 0.0055 | - |
pH 8.2, 37°C | Homo sapiens | Val-Thr-Val-Asn-Pro-Tyr-Lys-Trp-Leu-Pro | |
| 0.0058 | - |
pH 8.2, 37°C | Homo sapiens | Ile-Trp-His-His-Thr | |
| 0.0071 | - |
pH 8.2, 37°C | Homo sapiens | Val-Tyr | |
| 0.0098 | - |
pH 8.2, 37°C | Homo sapiens | Tyr-Ala-Leu-Pro-His-Ala | |
| 0.01 | - |
pH 8.2, 37°C | Homo sapiens | Ala-Leu-Pro-His-Ala | |
| 0.015 | - |
pH 8.2, 37°C | Homo sapiens | Thr-Val-Tyr | |
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