Literature summary for 3.4.15.1 extracted from

Santos, E.L.; de Picoli Souza, K.; Guimaraes, P.B.; Reis, F.C.; Silva, S.M.; Costa-Neto, C.M.; Luz, J.; Pesquero, J.B.
Effect of angiotensin converting enzyme inhibitor enalapril on body weight and composition in young rats (2008), Int. Immunopharmacol., 8, 247-253.

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Application

Application	Comment	Organism
medicine	modulation of the renin-angiotensin system by enalapril is important for body weight regulation and can be of beneficial effect in the treatment of obesity and related diseases	Rattus norvegicus

Inhibitors

Inhibitors	Comment	Organism	Structure
N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-L-proline	independent of diet enalapril treatment decreases food intake, energetic gain and body weight in normotensive young rats, followed by reduced body fat mass and serum leptin	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

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Release 2023.1 (January 2023)