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Literature summary for 3.4.15.1 extracted from
- Effects of genistein on angiotensin-converting enzyme in rats (2006), Life Sci., 79, 828-837.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | genistein has a potentially preventive role against cardiovascular diseases. Genistein inhibits the expression of angiotensin-converting enzyme via estrogen receptor and subsequently ERK1/2 signaling pathway in rat aortic endothelial cells. Down-regulation of the angiotensin-convering enzyme with a consequent change in circulating levels of angiotensin II, vasorelaxant angiotensin(1-7) and bradykinin plays an important role in cardiovascular effects of genistein through the ERK1/2 pathway | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| aorta | - |
Rattus norvegicus | - |
| aortic endothelial cell | - |
Rattus norvegicus | - |
| serum | - |
Rattus norvegicus | - |
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Release 2023.1 (January 2023)
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