Application | Comment | Organism |
---|---|---|
medicine | genistein has a potentially preventive role against cardiovascular diseases. Genistein inhibits the expression of angiotensin-converting enzyme via estrogen receptor and subsequently ERK1/2 signaling pathway in rat aortic endothelial cells. Down-regulation of the angiotensin-convering enzyme with a consequent change in circulating levels of angiotensin II, vasorelaxant angiotensin(1-7) and bradykinin plays an important role in cardiovascular effects of genistein through the ERK1/2 pathway | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
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Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
aorta | - |
Rattus norvegicus | - |
aortic endothelial cell | - |
Rattus norvegicus | - |
serum | - |
Rattus norvegicus | - |