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Literature summary for 3.4.15.1 extracted from

  • Araujo, M.C.; Melo, R.L.; Cesari, M.H.; Juliano, M.A.; Juliano, L.; Carmona, A.K.
    Peptidase specificity characterization of C- and N-terminal catalytic sites of angiotensin I-converting enzyme (2000), Biochemistry, 39, 8519-8525.
    View publication on PubMed
Search for more literature for 3.4.15.1

Protein Variants

Protein Variants Comment Organism
additional information substrate specificity characterization of two full-length mutant enzymes with either the N or C catalytic site inactivated by substitution of the two zinc-binding His by Lys (referred as N- or C-domains) Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
captopril
-
 Homo sapiens
EDTA 10 mM, complete inhibition of hydrolysis of o-aminobenzoyl-SDK-(dinitrophenyl)-P-OH and o-aminobenzoyl-FRK-(dinitrophenyl)-P-OH of wild-type enzyme, N-domain and C-domain Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00006
-
 o-aminobenzoyl-GFSPFQQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, N-domain Homo sapiens
0.0007
-
 o-aminobenzoyl-GFSPFRS-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
0.0007
-
 o-aminobenzoyl-GFSPFRF-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, N-domain Homo sapiens
0.0009
-
 o-aminobenzoyl-GFSPFRN-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
0.0009
-
 o-aminobenzoyl-GFSPFRR-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
0.0009
-
 o-aminobenzoyl-GFSPFQQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, C-domain Homo sapiens
0.001
-
 o-aminobenzoyl-GFSPFAQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, N-domain Homo sapiens
0.0011
-
 o-aminobenzoyl-GFSPFQQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
0.0011
-
 o-aminobenzoyl-GFSPFRF-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, C-domain Homo sapiens
0.0013
-
 o-aminobenzoyl-GFSPFRA-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
0.0013
-
 o-aminobenzoyl-GFSPFAQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
0.0014
-
 o-aminobenzoyl-GFSPFRF-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
0.0014
-
 o-aminobenzoyl-GFSPFRA-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, C-domain Homo sapiens
0.0014
-
 o-aminobenzoyl-GFSPFRR-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, C-domain Homo sapiens
0.0014
-
 o-aminobenzoyl-GFSPFRI-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, N-domain Homo sapiens
0.0014
-
 o-aminobenzoyl-GFSPFRR-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, N-domain Homo sapiens
0.0015
-
 o-aminobenzoyl-GFSPFRI-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
0.0016
-
 o-aminobenzoyl-GFSPFRQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
0.0016
-
 o-aminobenzoyl-GFSPFEQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
0.0018
-
 o-aminobenzoyl-GFSPFRA-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, N-domain Homo sapiens
0.002
-
 o-aminobenzoyl-GFSPFAQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, C-domain Homo sapiens
0.0021
-
 o-aminobenzoyl-GFSPFLQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
0.0021
-
 o-aminobenzoyl-GFSPFSQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, C-domain Homo sapiens
0.0023
-
 o-aminobenzoyl-GFSPFSQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, N-domain Homo sapiens
0.0024
-
 o-aminobenzoyl-GFSPFRI-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, C-domain Homo sapiens
0.0024
-
 o-aminobenzoyl-GFSPFFQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, N-domain Homo sapiens
0.0025
-
 o-aminobenzoyl-GFSPFSQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
0.0026
-
 o-aminobenzoyl-GFSPFFQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
0.0027
-
 o-aminobenzoyl-FRK-(dinitrophenyl)-P-OH pH 8.0, 37°C, C-domain Homo sapiens
0.003
-
 o-aminobenzoyl-GFSPFRS-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, C-domain Homo sapiens
0.003
-
 o-aminobenzoyl-GFSPFRS-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, N-domain Homo sapiens
0.003
-
 o-aminobenzoyl-GFSPFRQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, N-domain Homo sapiens
0.003
-
 o-aminobenzoyl-GFSPFLQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, N-domain Homo sapiens
0.0031
-
 o-aminobenzoyl-TRK-(dinitrophenyl)-P-OH pH 8.0, 37°C, N-domain Homo sapiens
0.0033
-
 o-aminobenzoyl-GFSPFRN-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, C-domain Homo sapiens
0.0034
-
 o-aminobenzoyl-GFSPFLQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, C-domain Homo sapiens
0.0034
-
 o-aminobenzoyl-FRK-(dinitrophenyl)-P-OH pH 8.0, 37°C, N-domain Homo sapiens
0.0037
-
 o-aminobenzoyl-GFSPFFQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, C-domain Homo sapiens
0.004
-
 o-aminobenzoyl-FRK-(dinitrophenyl)-P-OH pH 8.0, 37°C, wild-type enzyme Homo sapiens
0.0047
-
 o-aminobenzoyl-YRK-(dinitrophenyl)-P-OH pH 8.0, 37°C, C-domain Homo sapiens
0.005
-
 o-aminobenzoyl-GFSPFRN-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, N-domain Homo sapiens
0.005
-
 o-aminobenzoyl-YRK-(dinitrophenyl)-P-OH pH 8.0, 37°C, N-domain Homo sapiens
0.0051
-
 o-aminobenzoyl-YRK-(dinitrophenyl)-P-OH pH 8.0, 37°C, wild-type enzyme Homo sapiens
0.0051
-
 o-aminobenzoyl-YDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, N-domain Homo sapiens
0.006
-
 o-aminobenzoyl-GFSPFRQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, C-domain Homo sapiens
0.0074
-
 o-aminobenzoyl-TRK-(dinitrophenyl)-P-OH pH 8.0, 37°C, C-domain Homo sapiens
0.0102
-
 o-aminobenzoyl-TRK-(dinitrophenyl)-P-OH pH 8.0, 37°C, wild-type enzyme Homo sapiens
0.011
-
 o-aminobenzoyl-FDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, wild-type enzyme Homo sapiens
0.0111
-
 o-aminobenzoyl-YDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, wild-type enzyme Homo sapiens
0.0144
-
 o-aminobenzoyl-SRK-(dinitrophenyl)-P-OH pH 8.0, 37°C, N-domain Homo sapiens
0.0148
-
 o-aminobenzoyl-SRK-(dinitrophenyl)-P-OH pH 8.0, 37°C, wild-type enzyme Homo sapiens
0.015
-
 o-aminobenzoyl-YDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, C-domain Homo sapiens
0.0154
-
 o-aminobenzoyl-TDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, wild-type enzyme Homo sapiens
0.0157
-
 o-aminobenzoyl-TDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, N-domain Homo sapiens
0.017
-
 o-aminobenzoyl-SDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, wild-type enzyme Homo sapiens
0.0187
-
 o-aminobenzoyl-FDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, N-domain Homo sapiens
0.022
-
 o-aminobenzoyl-SDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, N-domain Homo sapiens
0.0229
-
 o-aminobenzoyl-SRK-(dinitrophenyl)-P-OH pH 8.0, 37°C, C-domain Homo sapiens
0.0248
-
 o-aminobenzoyl-FDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, C-domain Homo sapiens
0.032
-
 o-aminobenzoyl-SDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, C-domain Homo sapiens
0.0609
-
 o-aminobenzoyl-TDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, C-domain Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
o-aminobenzoyl-FDK-(dinitrophenyl)-P-OH + H2O
-
 Homo sapiens o-aminobenzoyl-FD + K-(dinitrophenyl)-P-OH
-
 ?
o-aminobenzoyl-FRK-(dinitrophenyl)-P-OH + H2O
-
 Homo sapiens o-aminobenzoyl-FR + K-(dinitrophenyl)-P-OH
-
 ?
o-aminobenzoyl-GFSPFAQ-(N-2,4-dinitrophenyl)ethylenediamine + H2O
-
 Homo sapiens o-aminobenzoyl-GFSPFA + Gln-(N-2,4-dinitrophenyl)ethylenediamine
-
 ?
o-aminobenzoyl-GFSPFEQ-(N-2,4-dinitrophenyl)ethylenediamine + H2O
-
 Homo sapiens o-aminobenzoyl-GFSPFE + Gln-(N-2,4-dinitrophenyl)ethylenediamine
-
 ?
o-aminobenzoyl-GFSPFFQ-(N-2,4-dinitrophenyl)ethylenediamine + H2O
-
 Homo sapiens o-aminobenzoyl-GFSPFF + Gln-(N-2,4-dinitrophenyl)ethylenediamine
-
 ?
o-aminobenzoyl-GFSPFLQ-(N-2,4-dinitrophenyl)ethylenediamine + H2O
-
 Homo sapiens o-aminobenzoyl-GFSPFL + Gln-(N-2,4-dinitrophenyl)ethylenediamine
-
 ?
o-aminobenzoyl-GFSPFQQ-(N-2,4-dinitrophenyl)ethylenediamine + H2O
-
 Homo sapiens o-aminobenzoyl-GFSPFQ + Gln-(N-2,4-dinitrophenyl)ethylenediamine
-
 ?
o-aminobenzoyl-GFSPFRA-(N-2,4-dinitrophenyl)ethylenediamine + H2O
-
 Homo sapiens o-aminobenzoyl-GFSPFR + Ala-(N-2,4-dinitrophenyl)ethylenediamine
-
 ?
o-aminobenzoyl-GFSPFRF-(N-2,4-dinitrophenyl)ethylenediamine + H2O
-
 Homo sapiens o-aminobenzoyl-GFSPFR + Phe-(N-2,4-dinitrophenyl)ethylenediamine
-
 ?
o-aminobenzoyl-GFSPFRI-(N-2,4-dinitrophenyl)ethylenediamine + H2O
-
 Homo sapiens o-aminobenzoyl-GFSPFR + Ile-(N-2,4-dinitrophenyl)ethylenediamine
-
 ?
o-aminobenzoyl-GFSPFRN-(N-2,4-dinitrophenyl)ethylenediamine + H2O
-
 Homo sapiens o-aminobenzoyl-GFSPFR + Asn-(N-2,4-dinitrophenyl)ethylenediamine
-
 ?
o-aminobenzoyl-GFSPFRQ-(N-2,4-dinitrophenyl)ethylenediamine + H2O
-
 Homo sapiens o-aminobenzoyl-GFSPFR + Gln-(N-2,4-dinitrophenyl)ethylenediamine
-
 ?
o-aminobenzoyl-GFSPFRR-(N-2,4-dinitrophenyl)ethylenediamine + H2O
-
 Homo sapiens o-aminobenzoyl-GFSPFR + Arg-(N-2,4-dinitrophenyl)ethylenediamine
-
 ?
o-aminobenzoyl-GFSPFRS-(N-2,4-dinitrophenyl)ethylenediamine + H2O
-
 Homo sapiens o-aminobenzoyl-GFSPFR + Ser-(N-2,4-dinitrophenyl)ethylenediamine
-
 ?
o-aminobenzoyl-GFSPFSQ-(N-2,4-dinitrophenyl)ethylenediamine + H2O
-
 Homo sapiens o-aminobenzoyl-GFSPFS + Gln-(N-2,4-dinitrophenyl)ethylenediamine
-
 ?
o-aminobenzoyl-SDK-(dinitrophenyl)-P-OH + H2O
-
 Homo sapiens o-aminobenzoyl-SD + K-(dinitrophenyl)-P-OH
-
 ?
o-aminobenzoyl-SRK-(dinitrophenyl)-P-OH + H2O
-
 Homo sapiens o-aminobenzoyl-SR + K-(dinitrophenyl)-P-OH
-
 ?
o-aminobenzoyl-TDK-(dinitrophenyl)-P-OH + H2O
-
 Homo sapiens o-aminobenzoyl-TD + K-(dinitrophenyl)-P-OH
-
 ?
o-aminobenzoyl-TRK-(dinitrophenyl)-P-OH + H2O
-
 Homo sapiens o-aminobenzoyl-TR + K-(dinitrophenyl)-P-OH
-
 ?
o-aminobenzoyl-YDK-(dinitrophenyl)-P-OH + H2O
-
 Homo sapiens o-aminobenzoyl-YD + K-(dinitrophenyl)-P-OH
-
 ?
o-aminobenzoyl-YRK-(dinitrophenyl)-P-OH + H2O
-
 Homo sapiens o-aminobenzoyl-YR + K-(dinitrophenyl)-P-OH
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.06
-
 o-aminobenzoyl-TDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, C-domain Homo sapiens
0.1
-
 o-aminobenzoyl-SDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, C-domain Homo sapiens
0.2
-
 o-aminobenzoyl-TRK-(dinitrophenyl)-P-OH pH 8.0, 37°C, C-domain Homo sapiens
0.3
-
 o-aminobenzoyl-GFSPFQQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, C-domain Homo sapiens
0.6
-
 o-aminobenzoyl-GFSPFQQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, N-domain Homo sapiens
0.8
-
 o-aminobenzoyl-GFSPFSQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, C-domain Homo sapiens
0.9
-
 o-aminobenzoyl-GFSPFRS-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
0.9
-
 o-aminobenzoyl-GFSPFRR-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, N-domain Homo sapiens
1
-
 o-aminobenzoyl-GFSPFRR-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
1
-
 o-aminobenzoyl-GFSPFRF-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, N-domain Homo sapiens
1
-
 o-aminobenzoyl-GFSPFAQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, N-domain Homo sapiens
1.01
-
 o-aminobenzoyl-YRK-(dinitrophenyl)-P-OH pH 8.0, 37°C, wild-type enzyme Homo sapiens
1.1
-
 o-aminobenzoyl-TDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, N-domain Homo sapiens
1.3
-
 o-aminobenzoyl-GFSPFRS-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, N-domain Homo sapiens
1.4
-
 o-aminobenzoyl-GFSPFRF-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, C-domain Homo sapiens
1.4
-
 o-aminobenzoyl-GFSPFRR-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, C-domain Homo sapiens
1.8
-
 o-aminobenzoyl-GFSPFRN-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
2
-
 o-aminobenzoyl-GFSPFQQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
2
-
 o-aminobenzoyl-GFSPFSQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
2
-
 o-aminobenzoyl-GFSPFAQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, C-domain Homo sapiens
2.2
-
 o-aminobenzoyl-GFSPFRQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
2.2
-
 o-aminobenzoyl-GFSPFEQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
2.3
-
 o-aminobenzoyl-GFSPFSQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, N-domain Homo sapiens
2.4
-
 o-aminobenzoyl-GFSPFRS-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, C-domain Homo sapiens
2.4
-
 o-aminobenzoyl-GFSPFFQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, N-domain Homo sapiens
2.6
-
 o-aminobenzoyl-GFSPFRI-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, N-domain Homo sapiens
2.7
-
 o-aminobenzoyl-GFSPFRQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, N-domain Homo sapiens
2.9
-
 o-aminobenzoyl-GFSPFRI-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, C-domain Homo sapiens
3
-
 o-aminobenzoyl-GFSPFLQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, N-domain Homo sapiens
3.3
-
 o-aminobenzoyl-GFSPFAQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
3.3
-
 o-aminobenzoyl-GFSPFRN-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, C-domain Homo sapiens
3.4
-
 o-aminobenzoyl-GFSPFRA-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, N-domain Homo sapiens
3.7
-
 o-aminobenzoyl-GFSPFLQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
3.8
-
 o-aminobenzoyl-GFSPFRN-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, N-domain Homo sapiens
4.2
-
 o-aminobenzoyl-GFSPFRF-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
4.2
-
 o-aminobenzoyl-GFSPFRQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, C-domain Homo sapiens
4.8
-
 o-aminobenzoyl-GFSPFLQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, C-domain Homo sapiens
5
-
 o-aminobenzoyl-GFSPFRA-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, C-domain Homo sapiens
7
-
 o-aminobenzoyl-YDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, C-domain Homo sapiens
8.7
-
 o-aminobenzoyl-GFSPFRI-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
10.1
-
 o-aminobenzoyl-GFSPFFQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
10.4
-
 o-aminobenzoyl-GFSPFRA-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, wild-type enzyme Homo sapiens
12.6
-
 o-aminobenzoyl-GFSPFFQ-(N-2,4-dinitrophenyl)ethylenediamine pH 8.0, 37°C, C-domain Homo sapiens
13.7
-
 o-aminobenzoyl-SRK-(dinitrophenyl)-P-OH pH 8.0, 37°C, C-domain Homo sapiens
13.9
-
 o-aminobenzoyl-TRK-(dinitrophenyl)-P-OH pH 8.0, 37°C, N-domain Homo sapiens
18.7
-
 o-aminobenzoyl-TDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, N-domain Homo sapiens
24.6
-
 o-aminobenzoyl-SDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, N-domain Homo sapiens
26.7
-
 o-aminobenzoyl-FRK-(dinitrophenyl)-P-OH pH 8.0, 37°C, wild-type enzyme Homo sapiens
28.6
-
 o-aminobenzoyl-SRK-(dinitrophenyl)-P-OH pH 8.0, 37°C, N-domain Homo sapiens
28.9
-
 o-aminobenzoyl-YDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, N-domain Homo sapiens
31
-
 o-aminobenzoyl-FDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, C-domain Homo sapiens
36.3
-
 o-aminobenzoyl-TDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, wild-type enzyme Homo sapiens
44.2
-
 o-aminobenzoyl-SDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, wild-type enzyme Homo sapiens
54.9
-
 o-aminobenzoyl-FRK-(dinitrophenyl)-P-OH pH 8.0, 37°C, N-domain Homo sapiens
58.8
-
 o-aminobenzoyl-YRK-(dinitrophenyl)-P-OH pH 8.0, 37°C, C-domain Homo sapiens
62.5
-
 o-aminobenzoyl-YDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, wild-type enzyme Homo sapiens
69.2
-
 o-aminobenzoyl-FRK-(dinitrophenyl)-P-OH pH 8.0, 37°C, C-domain Homo sapiens
79
-
 o-aminobenzoyl-FDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, N-domain Homo sapiens
79.9
-
 o-aminobenzoyl-FDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, wild-type enzyme Homo sapiens
82
-
 o-aminobenzoyl-TRK-(dinitrophenyl)-P-OH pH 8.0, 37°C, wild-type enzyme Homo sapiens
85.6
-
 o-aminobenzoyl-YRK-(dinitrophenyl)-P-OH pH 8.0, 37°C, N-domain Homo sapiens
101.7
-
 o-aminobenzoyl-FDK-(dinitrophenyl)-P-OH pH 8.0, 37°C, N-domain Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
 hydrolysis of o-aminobenzoyl-FRK-(dinitrophenyl)-P-OH Homo sapiens

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.000009
-
 captopril pH 8.0, 37°C, N-domain, hydrolysis of o-aminobenzoyl-SDK-(dinitrophenyl)-P-OH Homo sapiens
0.00001
-
 captopril pH 8.0, 37°C, wild-type enzyme, hydrolysis of o-aminobenzoyl-SDK-(dinitrophenyl)-P-OH Homo sapiens
0.000016
-
 captopril pH 8.0, 37°C, C-domain, hydrolysis of o-aminobenzoyl-FRK-(dinitrophenyl)-P-OH Homo sapiens
0.000025
-
 captopril pH 8.0, 37°C, N-domain, hydrolysis of o-aminobenzoyl-FRK-(dinitrophenyl)-P-OH Homo sapiens
0.000046
-
 captopril pH 8.0, 37°C, wild-type enzyme, hydrolysis of o-aminobenzoyl-FRK-(dinitrophenyl)-P-OH Homo sapiens
0.000191
-
 captopril pH 8.0, 37°C, C-domain, hydrolysis of o-aminobenzoyl-SDK-(dinitrophenyl)-P-OH Homo sapiens