Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ASP8497 | i.e. (2S,4S)-4-fluoro-1-([[4-methyl-1-(methylsulfonyl)-piperidin-4-yl]amino]acetyl)pyrrolidine-2-carbonitrile monofumarate, potent and long-acting inhibitor of plasma DPP-IV activity, inhibitory activity lasts up to 24 h when administered at 5 mg/kg twice a day or 10 mg/kg once a day | Mus musculus | |
saxagliptin | BMS-477178, (1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxy-1-adamantyl)acetyl]-2-azabicyclo[3.1.0]-hexane-3-carbonitrile hydrochloride | Mus musculus | |
sitagliptin | MK-0431, (2 R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo-[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine phosphate | Mus musculus | |
vildagliptin | LAF237, 1-[[(3-hydroxy-1-adamantyl)-amino]acetyl]-2-cyano-(S)-pyrrolidine | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
glucagon-like peptide 1 + H2O | Mus musculus | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood plasma | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glucagon-like peptide 1 + H2O | - |
Mus musculus | ? | - |
? | |
Gly-L-Pro-7-amido-4-methylcoumarin + H2O | - |
Mus musculus | Gly-L-Pro + 7-amino-4-methylcoumarin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
dipeptidyl peptidase-IV | - |
Mus musculus |
DPP-IV | - |
Mus musculus |