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Literature summary for 3.4.14.5 extracted from

  • Dai, H.; Gustavson, S.M.; Preston, G.M.; Eskra, J.D.; Calle, R.; Hirshberg, B.
    Non-linear increase in GLP-1 levels in response to DPP-IV inhibition in healthy adult subjects (2008), Diabetes Obes. Metab., 10, 506-513.
    View publication on PubMed
Search for more literature for 3.4.14.5

Inhibitors

Inhibitors Comment Organism Structure
PF-00734200 potent, competitive DPP-IV inhibitor, complete inhibition of DPP-IV for over 24 h after treatment with one single dose of 300 mg PF-00734200 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
glucagon-like peptide 1 + H2O Homo sapiens
-
 ?
-
 ?
glucose-dependent insulinotropic peptide + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glucagon-like peptide 1 + H2O
-
 Homo sapiens ?
-
 ?
glucose-dependent insulinotropic peptide + H2O
-
 Homo sapiens ?
-
 ?
Gly-L-Pro-7-amido-4-methylcoumarin + H2O
-
 Homo sapiens Gly-L-Pro + 7-amino-4-methylcoumarin
-
 ?

Synonyms

Synonyms Comment Organism
dipeptidyl peptidase-IV
-
 Homo sapiens
DPP-IV
-
 Homo sapiens