Literature summary for 3.4.14.5 extracted from

Davoodi, J.; Kelly, J.; Gendron, N.H.; MacKenzie, A.E.
The Simpson-Golabi-Behmel syndrome causative glypican-3, binds to and inhibits the dipeptidyl peptidase activity of CD26 (2007), Proteomics, 7, 2300-2310.

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Inhibitors

Inhibitors	Comment	Organism	Structure
glypican-3	Simpson-Golabi-Behmel syndrome is an X-linked condition shown to be the result of deletions of the glypican-3 gene. Glypican-3, binds to and inhibits the dipeptidyl peptidase activity of CD26. Inhibition of CD26 reduces the rate of cell proliferation. A number of physical findings observed in SGBS patients may be a consequence of a direct interaction of GPC3 with CD26	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
Hep-G2/C3A cell	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
CD26 peptidase	-	Homo sapiens

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Release 2023.1 (January 2023)