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Literature summary for 3.4.14.5 extracted from

  • Campbell, T.B.; Broxmeyer, H.E.
    CD26 inhibition and hematopoiesis: a novel approach to enhance transplantation (2008), Front. Biosci., 13, 1795-1805.
    View publication on PubMed

Application

Application Comment Organism
medicine CD26 inhibition may represent a novel approach to increasing the efficacy and success of hematopoietic stem cell/hematopoietic progenitor cell transplantation, especially under conditions of limiting donor cell yield Mus musculus
medicine CD26 inhibition may represent a novel approach to increasing the efficacy and success of hematopoietic stem cell/hematopoietic progenitor cell transplantation, especially under conditions of limiting donor cell yield Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
Diprotin A
-
Homo sapiens
Diprotin A
-
Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cell surface
-
Mus musculus 9986
-
cell surface
-
Homo sapiens 9986
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
SDF-1/CXCL12 + H2O Mus musculus CD26 may play a role in SDF-1/CXCL12 mediated functions such as chemotaxis ?
-
?
SDF-1/CXCL12 + H2O Homo sapiens CD26 may play a role in SDF-1/CXCL12 mediated functions such as chemotaxis ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
bone marrow
-
Mus musculus
-
hematopoietic stem cell
-
Mus musculus
-
hematopoietic stem cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
SDF-1/CXCL12 + H2O CD26 may play a role in SDF-1/CXCL12 mediated functions such as chemotaxis Mus musculus ?
-
?
SDF-1/CXCL12 + H2O CD26 may play a role in SDF-1/CXCL12 mediated functions such as chemotaxis Homo sapiens ?
-
?
SDF-1/CXCL12 + H2O CD26 can cleave SDF-1/CXCL12 to a chemotactically-null molecule Mus musculus ?
-
?
SDF-1/CXCL12 + H2O CD26 can cleave SDF-1/CXCL12 to a chemotactically-null molecule Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
dipeptidylpeptidase IV/CD26
-
Mus musculus
dipeptidylpeptidase IV/CD26
-
Homo sapiens