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Literature summary for 3.4.14.5 extracted from

  • He, Y.L.; Sabo, R.; Riviere, G.J.; Sunkara, G.; Leon, S.; Ligueros-Saylan, M.; Rosenberg, M.; Dole, W.P.; Howard, D.
    Effect of the novel oral dipeptidyl peptidase IV inhibitor vildagliptin on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects (2007), Curr. Med. Res. Opin., 23, 1131-1138.
    View publication on PubMed

Application

Application Comment Organism
medicine the dipeptidyl peptidase-IV inhibitor vildagliptin improves glycemic control in patients with type 2 diabetes by increasing alpha and beta-cell responsiveness to glucose. Co-administration of warfarin (a vitamin K antagonist widely used for long-term prevention of thrombosis) does not alter the pharmacokinetics of vildagliptin Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
vildagliptin
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Synonyms

Synonyms Comment Organism
dipeptidyl peptidase-IV
-
Homo sapiens
DPP-4
-
Homo sapiens