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Literature summary for 3.4.14.5 extracted from
- Characterization and cDNA cloning of dipeptidyl peptidase IV from the venom of Gloydius blomhoffi brevicaudatus (2006), Comp. Biochem. Physiol. B, 145, 35-42.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Gloydius brevicaudus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| diisopropylfluorophosphate | 1 mM, complete inhibition; 1 mM, complete inhibition | Gloydius brevicaudus |  |
| additional information | no inhibition by 5 mM EDTA or 0.005 mg/ml leupeptin; no inhibition by 5 mM EDTA or 0.005 mg/ml leupeptin | Gloydius brevicaudus |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 116000 | - |
x * 116000, SDS-PAGE | Gloydius brevicaudus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Gloydius brevicaudus | Q75S82 | dipeptidylpeptidase 4b | - |
| Gloydius brevicaudus | Q75S83 | dipeptidylpeptidase 4a | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Gloydius brevicaudus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| venom | - |
Gloydius brevicaudus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.0598 | - |
- |
Gloydius brevicaudus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Gly-Pro-4-methylcoumarin 7-amide + H2O | - |
Gloydius brevicaudus | Gly-Pro + 7-amino-4-methylcoumarin | - |
? | |
| Lys-Ala-4-methylcoumarin 7-amide + H2O | 8.7% of the activity with Pro-4-methylcoumarin 7-amide | Gloydius brevicaudus | Lys-Ala + 7-amino-4-methylcoumarin | - |
? | |
| Phe-Pro-4-methylcoumarin 7-amide + H2O | 108.6% of the activity with Pro-4-methylcoumarin 7-amide | Gloydius brevicaudus | Phe-Pro + 7-amino-4-methylcoumarin | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 116000, SDS-PAGE | Gloydius brevicaudus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| dipeptidylpeptidase 4a | - |
Gloydius brevicaudus |
| dipeptidylpeptidase 4b | - |
Gloydius brevicaudus |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 50 | - |
stable up to | Gloydius brevicaudus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.5 | - |
- |
Gloydius brevicaudus |
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