Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.14.5 extracted from

  • Lorey, S.; Faust, J.; Buhling, F.; Ansorge, S.; Neubert, K.
    A new type of fluorogenic substrates for determination of cellular dipeptidyl peptidase IV (DP IV/CD26) activity (2000), Adv. Exp. Med. Biol., 477, 111-115.
    View publication on PubMed
Search for more literature for 3.4.14.5

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00058
-
 N-(Ala-Pro)-N'-6-(3,4-dichloromaleimidyl)-hexanoyl-rhodamine 110
-
 Sus scrofa
0.0011
-
 N-(Gly-Pro)-N'-(4-chloromethyl)benzoyl-rhodamine 110
-
 Sus scrofa
0.0013
-
 Gly-L-Pro-rhodamine 110-(N-pentyl)maleimide
-
 Sus scrofa
0.0015
-
 N-(Gly-Pro)-N'-(5-bromopentanoyl)-rhodamine 110
-
 Sus scrofa
0.0027
-
 N-(Gly-Pro)-N'-4-(maleimidyl)butanoyl-rhodamine 110
-
 Sus scrofa
0.0038
-
 N-(Gly-Pro)-N'-(4-chlorobutanoyl)-rhodamine 110
-
 Sus scrofa
0.0038
-
 N-(Gly-Pro)-N'-(5-chloropentanoyl)-rhodamine 110
-
 Sus scrofa
0.0062
-
 N-(Gly-Pro)-N'-chloroacetyl-rhodamine 110
-
 Sus scrofa
0.0174
-
 N-(Gly-Pro)-N'-acetyl-rhodamine 110
-
 Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane bound, type II Sus scrofa 16020
-

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein type II Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
epithelium
-
 Sus scrofa
-
kidney
-
 Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gly-L-Pro-rhodamine 110-(N-pentyl)maleimide + H2O
-
 Sus scrofa Gly-L-Pro + rhodamine 110-(N-pentyl)maleimide
-
 ?
N-(Ala-Pro)-N'-6-(3,4-dichloromaleimidyl)-hexanoyl-rhodamine 110 + H2O fluorogenic substrate Sus scrofa Ala-Pro + N-6-(3,4-dichloromaleimidyl)-hexanoyl-rhodamine 110
-
 ?
N-(Gly-Pro)-N'-(4-chlorobutanoyl)-rhodamine 110 + H2O fluorogenic substrate Sus scrofa Gly-Pro + N-(4-chlorobutanoyl)-rhodamine 110
-
 ?
N-(Gly-Pro)-N'-(4-chloromethyl)benzoyl-rhodamine 110 + H2O fluorogenic substrate Sus scrofa Gly-Pro + N-(4-chloromethyl)benzoyl-rhodamine 110
-
 ?
N-(Gly-Pro)-N'-(5-bromopentanoyl)-rhodamine 110 + H2O fluorogenic substrate Sus scrofa Gly-Pro + N-(5-bromopentanoyl)-rhodamine 110
-
 ?
N-(Gly-Pro)-N'-(5-chloropentanoyl)-rhodamine 110 + H2O fluorogenic substrate Sus scrofa Gly-Pro + N-(5-chloropentanoyl)-rhodamine 110
-
 ?
N-(Gly-Pro)-N'-4-(maleimidyl)butanoyl-rhodamine 110 + H2O fluorogenic substrate Sus scrofa Gly-Pro + N-4-(maleimidyl)butanoyl-rhodamine 110
-
 ?
N-(Gly-Pro)-N'-6-(maleimidyl)hexanoyl-rhodamine 110 + H2O fluorogenic substrate Sus scrofa Gly-Pro + N-6-(maleimidyl)hexanoyl-rhodamine 110
-
 ?
N-(Gly-Pro)-N'-acetyl-rhodamine 110 + H2O fluorogenic substrate Sus scrofa Gly-Pro + N-acetyl-rhodamine 110
-
 ?
N-(Gly-Pro)-N'-chloroacetyl-rhodamine 110 + H2O fluorogenic substrate Sus scrofa Gly-Pro + N-chloroacetyl-rhodamine 110
-
 ?

Synonyms

Synonyms Comment Organism
CD26
-
 Sus scrofa
dipeptidyl peptidase IV
-
 Sus scrofa
DP IV
-
 Sus scrofa

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 in vitro assay at Sus scrofa
37
-
 in vivo assay at Sus scrofa

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.55
-
 N-(Ala-Pro)-N'-6-(3,4-dichloromaleimidyl)-hexanoyl-rhodamine 110
-
 Sus scrofa
0.7
-
 N-(Gly-Pro)-N'-(4-chlorobutanoyl)-rhodamine 110
-
 Sus scrofa
1.6
-
 N-(Gly-Pro)-N'-chloroacetyl-rhodamine 110
-
 Sus scrofa
3.22
-
 N-(Gly-Pro)-N'-(5-bromopentanoyl)-rhodamine 110
-
 Sus scrofa
3.4
-
 N-(Gly-Pro)-N'-(4-chloromethyl)benzoyl-rhodamine 110
-
 Sus scrofa
8
-
 N-(Gly-Pro)-N'-4-(maleimidyl)butanoyl-rhodamine 110
-
 Sus scrofa
8
-
 N-(Gly-Pro)-N'-(5-chloropentanoyl)-rhodamine 110
-
 Sus scrofa