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Literature summary for 3.4.14.5 extracted from
- Human serum dipeptidyl peptidase IV (DPPIV) and its unique properties (1996), J. Clin. Lab. Anal., 10, 435-440.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Gln | activates | Homo sapiens |  |
| Glu | activates | Homo sapiens | |
| Gly | activates | Homo sapiens | |
| Gly-X dipeptides | enhance activity | Homo sapiens | |
| glycine methylesters | activates | Homo sapiens | |
| Ser | activates | Homo sapiens | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Cd2+ | CdCl2 | Homo sapiens | |
| Diprotin A | - |
Homo sapiens | |
| Hg2+ | HgCl2 | Homo sapiens | |
| Leu | - |
Homo sapiens | |
| Lys | - |
Homo sapiens | |
| Met | - |
Homo sapiens | |
| PCMB | - |
Homo sapiens | |
| SrCl2 | - |
Homo sapiens | |
| Zn2+ | ZnCl2 | Homo sapiens | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.17 | - |
Gly-Pro-3,5-dibromo-4-hydroxyanilide | - |
Homo sapiens | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 100000 | - |
2 * 100000, SDS-PAGE | Homo sapiens |
| 230000 | 250000 | gel filtration | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| serum | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Gly-azetidine-2-carboxyl-3,5-dibromo-4-hydroxyanilide + H2O | - |
Homo sapiens | Gly-azetidine + 3,5-dibromo-4-hydroxyaniline | - |
? | |
| Gly-L-hydroxyproline-3,5-dibromo-4-hydroxyanilide + H2O | - |
Homo sapiens | Gly-L-hydroxyproline + 3,5-dibromo-4-hydroxyaniline | - |
? | |
| Gly-Pro-3,5-dibromo-4-hydroxyanilide + H2O | - |
Homo sapiens | Gly-Pro + 3,5-dibromo-4-hydroxyaniline | - |
? | |
| Gly-Pro-4-nitroanilide + H2O | - |
Homo sapiens | Gly-Pro + 4-nitroaniline | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 100000, SDS-PAGE | Homo sapiens |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 810 | - |
Gly-Pro-3,5-dibromo-4-hydroxyanilide | - |
Homo sapiens | |
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