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Literature summary for 3.4.14.5 extracted from

  • Svensson, B.; Danielsen, M.; Staun, M.; Jeppesen, L.; Noren, O.; Sjöström, H.
    An amphiphilic form of dipeptidyl peptidase IV from pig small-intestinal brush-border membrane. Purification by immunoadsorbent chromatography and some properties (1978), Eur. J. Biochem., 90, 489-498.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Gly-L-Pro competitive inhibition of hydrolysis of Gly-L-Pro-4-nitroanilide Sus scrofa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.24
-
Gly-L-Pro-4-nitroanilide
-
Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
137000
-
2 * 137000, SDS-PAGE Sus scrofa
230000
-
gel filtration Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
small intestine brush-border membrane Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Ala-4-nitroanilide + H2O low activity Sus scrofa Ala + 4-nitroaniline
-
?
Ala-Ala-2-naphthylamide + H2O
-
Sus scrofa Ala-Ala + 2-naphthylamine
-
?
Ala-Ala-Ala + H2O
-
Sus scrofa Ala-Ala + Ala
-
?
Gly-L-Pro-4-nitroanilide + H2O
-
Sus scrofa Gly-L-Pro + 4-nitroaniline
-
?
Gly-L-Pro-L-Ala + H2O
-
Sus scrofa Gly-L-Pro + L-Ala
-
?
Gly-Pro-2-naphthylamide + H2O
-
Sus scrofa Gly-Pro + 2-naphthylamine
-
?
Gly-Pro-4-nitroanilide + H2O
-
Sus scrofa Gly-Pro + 4-nitroaniline
-
?
L-Ala-L-Ala-L-Ala-L-Ala + H2O
-
Sus scrofa L-Ala-L-Ala
-
?
L-Leu-L-Leu-L-Val-L-Tyr-L-Ser + H2O
-
Sus scrofa Leu-Leu + Val-Tyr + Ser
-
?

Subunits

Subunits Comment Organism
dimer 2 * 137000, SDS-PAGE Sus scrofa