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Literature summary for 3.4.14.4 extracted from

  • Abramic, M.; Karacic, Z.; Semanjski, M.; Vukelic, B.; Jajcanin-Jozic, N.
    Aspartate 496 from the subsite S2 drives specificity of human dipeptidyl peptidase III (2015), Biol. Chem., 396, 359-366.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
D496G mutation in S2 subsite, mutant has lost selectivity due to the increase of the Km value. Mutant shows significantly decreased binding of peptides with N-terminal arginine, and of tynorphin Homo sapiens
S504G mutation in S2 subsite, mutant does not show decreased binding of peptides with N-terminal arginine Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Homo sapiens
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