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Literature summary for 3.4.14.4 extracted from

  • Shimamori, Y.; Watanabe, Y.; Fujimoto, Y.
    Purification and characterization of dipeptidyl aminopeptidase III from human placenta (1986), Chem. Pharm. Bull., 34, 3333-3340.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
5,5'-dithiobis(2-nitrobenzoate) reactivation by DTT or 2-mercaptoethanol Homo sapiens
EDTA
-
Homo sapiens
Ni2+
-
Homo sapiens
Zn2+
-
Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.038
-
Arg-Arg-2-naphthylamide
-
Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
80000 86000 gel filtration Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
placenta
-
Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Homo sapiens

Storage Stability

Storage Stability Organism
-80°C Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Ala-Arg-2-naphthylamide + H2O
-
Homo sapiens Ala-Arg + 2-naphthylamine
-
?
Arg-Arg-2-naphthylamide + H2O
-
Homo sapiens Arg-Arg + 2-naphthylamine
-
?
Leu-Gly-2-naphthylamide + H2O
-
Homo sapiens Leu-Gly + 2-naphthylamine
-
?

Subunits

Subunits Comment Organism
monomer 1 * ?, SDS-PAGE Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
9
-
substrate Arg-Arg-p-nitroanilide or Arg-Arg-2-naphthylamide Homo sapiens