Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.14.14 extracted from

  • Ayikpoe, R.; Salazar, J.; Majestic, B.; Latham, J.A.
    Mycofactocin biosynthesis proceeds through 3-amino-5-[( p-hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidinone (AHDP); direct observation of MftE specificity toward MftA (2018), Biochemistry, 57, 5379-5383 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.14.14

Metals/Ions

Metals/Ions Comment Organism Structure
Fe2+ dependent on Mycolicibacterium smegmatis
Fe2+ dependent on Mycobacterium ulcerans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mycolicibacterium smegmatis the enzyme does not recognize the unmodified peptide MftA nor the intermediate MftA-glycyl-N-[(E)-2-(4-hydroxyphenyl)ethenyl]-L-valinamide ?
-
-
additional information Mycobacterium ulcerans the enzyme does not recognize the unmodified peptide MftA nor the intermediate MftA-glycyl-N-[(E)-2-(4-hydroxyphenyl)ethenyl]-L-valinamide ?
-
-
precursor peptide MftA-glycyl-3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one + H2O Mycolicibacterium smegmatis the enzyme is specific for MftA-glycyl-3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one MftA(1-28) + 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidinone
-
 ?
precursor peptide MftA-glycyl-3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one + H2O Mycobacterium ulcerans the enzyme is specific for MftA-glycyl-3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one MftA(1-28) + 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidinone
-
 ?

Organism

Organism UniProt Comment Textmining
Mycobacterium ulcerans
-
-
-
Mycolicibacterium smegmatis
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme does not recognize the unmodified peptide MftA nor the intermediate MftA-glycyl-N-[(E)-2-(4-hydroxyphenyl)ethenyl]-L-valinamide Mycolicibacterium smegmatis ?
-
-
additional information the enzyme does not recognize the unmodified peptide MftA nor the intermediate MftA-glycyl-N-[(E)-2-(4-hydroxyphenyl)ethenyl]-L-valinamide Mycobacterium ulcerans ?
-
-
precursor peptide MftA-glycyl-3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one + H2O the enzyme is specific for MftA-glycyl-3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one Mycolicibacterium smegmatis MftA(1-28) + 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidinone
-
 ?
precursor peptide MftA-glycyl-3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one + H2O the enzyme is specific for MftA-glycyl-3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one Mycobacterium ulcerans MftA(1-28) + 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidinone
-
 ?

Synonyms

Synonyms Comment Organism
mftE
-
 Mycolicibacterium smegmatis
mftE
-
 Mycobacterium ulcerans