Literature summary for 3.4.14.10 extracted from

Schnurr, M.; Orban, M.; Robson, N.C.; Shin, A.; Braley, H.; Airey, D.; Cebon, J.; Maraskovsky, E.; Endres, S.
ISCOMATRIX adjuvant induces efficient cross-presentation of tumor antigen by dendritic cells via rapid cytosolic antigen delivery and processing via tripeptidyl peptidase II (2009), J. Immunol., 182, 1253-1259.

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Inhibitors

Inhibitors	Comment	Organism	Structure
butabindide oxalate	specific TPPII inhibitor	Homo sapiens
L-Ala-L-Ala-L-Phe-chloromethylketone	-	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytosol	-	Homo sapiens	5829	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	tripeptidyl peptidase II plays a role in cross-presentation of CTL epitopes restricted to diverse HLA alleles	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
monocyte-derived dendritic cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	tripeptidyl peptidase II plays a role in cross-presentation of CTL epitopes restricted to diverse HLA alleles	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
TPP II	-	Homo sapiens
tripeptidyl peptidase II	-	Homo sapiens

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Release 2023.1 (January 2023)