Cloned (Comment) | Organism |
---|---|
- |
Drosophila melanogaster |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
butabindide | 0.002 mM, 83% inhibition | Drosophila melanogaster | |
butabindide | - |
Rattus norvegicus | |
NEM | 1 mM, 87% inhibition | Drosophila melanogaster | |
PCMB | 0.2 mM, 97% inhibition | Drosophila melanogaster | |
PMSF | 1 mM nearly complete inactivation | Drosophila melanogaster |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | cholecystokinin-8-inactivating peptidase is a membrane bound isoform | Rattus norvegicus | 16020 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
150000 | - |
gel filtration | Drosophila melanogaster |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila melanogaster | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Drosophila melanogaster |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cerebellum | - |
Rattus norvegicus | - |
embryo | higher specific activity in extracts from embryos as compared with adult | Drosophila melanogaster | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Drosophila melanogaster |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Ala-Ala-Ala-p-nitroanilide + H2O | 24% of the activity with Ala-Ala-Phe-p-nitroanilide | Drosophila melanogaster | Ala-Ala-Ala + p-nitroaniline | - |
? | |
Ala-Ala-Phe-p-nitroanilide + H2O | - |
Drosophila melanogaster | Ala-Ala-Phe + p-nitroaniline | - |
? | |
Gly-Val-Leu-Arg-Arg-Ala-Ser-Val-Ala + H2O | - |
Drosophila melanogaster | Gly-Val-Leu + Arg-Arg-Ala-Ser-Val-Ala | - |
? | |
Pro-Pro-Ala-p-nitroanilide + H2O | 12% of the activity with Ala-Ala-Phe-p-nitroanilide | Drosophila melanogaster | Pro-Pro-Ala-p-nitroaniline | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | 7.8 | reaction with Ala-Ala-Phe-p-nitroanilide | Drosophila melanogaster |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0001 | - |
butabindide | pH 7.5, 37°C | Drosophila melanogaster |