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Literature summary for 3.4.11.6 extracted from
- Aminopeptidase B in the rat testes: isolation, functional properties and cellular localization in the seminiferous tubules (1995), Mol. Cell. Endocrinol., 110, 149-160.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,10-phenanthroline | - |
Rattus norvegicus |  |
| arphamenine A | - |
Rattus norvegicus | |
| Arphamenine B | - |
Rattus norvegicus | |
| bestatin | - |
Rattus norvegicus | |
| dithiothreitol | - |
Rattus norvegicus | |
| EDTA | - |
Rattus norvegicus | |
| EGTA | - |
Rattus norvegicus | |
| N-ethylmaleimide | - |
Rattus norvegicus | |
| N-[(2S,3R)-3-amino-2-hydroxy-5-methylhexanoyl]-L-valyl-L-valyl-L-aspartic acid | - |
Rattus norvegicus | |
| N-[1-(R,S)-carboxy-3-phenyl propyl] Ala-Ala-Phe-p-aminobenzoate | - |
Rattus norvegicus | |
| NaI | - |
Rattus norvegicus | |
| p-chloromercuribenzene sulfonic acid | - |
Rattus norvegicus | |
| p-chloromercuribenzoate | - |
Rattus norvegicus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | - |
Rattus norvegicus | |
| 0.02 | - |
L-Arg-beta-naphthylamide | - |
Rattus norvegicus | |
| 0.36 | - |
L-Lys-beta-naphthylamide | - |
Rattus norvegicus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| KCl | activation | Rattus norvegicus | |
| NaCl | activation | Rattus norvegicus | |
| Zn2+ | restores activity after inhibition with 1,10-phenanthroline | Rattus norvegicus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 72000 | - |
1 * 72000, SDS-PAGE | Rattus norvegicus |
| 72000 | 75000 | gel filtration | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| testis | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-Arg-2-naphthylamide + H2O | - |
Rattus norvegicus | L-Arg + 2-naphthylamine | - |
? | |
| Lys-2-naphthylamide + H2O | - |
Rattus norvegicus | Lys + 2-naphthylamine | - |
? | |
| additional information | - |
Rattus norvegicus | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 72000, SDS-PAGE | Rattus norvegicus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 5.5 | 8.25 | - |
Rattus norvegicus |
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