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Literature summary for 3.4.11.5 extracted from

  • Maekinen, K.K.; Syed, S.A.; Maekinen, P.L.; Loesche, W.J.
    Dominance of inminopeptidase activity in the human oral bacterium Treponema denticola ATCC 35405 (1987), Curr. Microbiol., 14, 341-346.
No PubMed abstract available

Activating Compound

Activating Compound Comment Organism Structure
dithiothreitol restores activity after deactivation with p-chloromercuribenzoate Treponema denticola

Inhibitors

Inhibitors Comment Organism Structure
1-(Ethoxycarbonyl)-2-ethoxy-1,2-dihydroquinone
-
Treponema denticola
Diazotized sulfanilic acid
-
Treponema denticola
diethyldicarbonate
-
Treponema denticola
p-chloromercuribenzoate
-
Treponema denticola
Phenylmethylsulfonylfluoride
-
Treponema denticola
Tetranitromethane
-
Treponema denticola

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Treponema denticola 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
100000
-
? * 100000, SDS-PAGE Treponema denticola

Organism

Organism UniProt Comment Textmining
Treponema denticola
-
ATCC 35405
-

Purification (Commentary)

Purification (Comment) Organism
partial, 3 enzymes: I, II, III Treponema denticola

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Treponema denticola
0.48
-
type III Treponema denticola

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-L-Pro-2-naphthylamide + H2O
-
Treponema denticola L-proline + naphthylamine
-
?

Subunits

Subunits Comment Organism
More ? * 100000, SDS-PAGE Treponema denticola

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7 7.5 enzyme III Treponema denticola
7 8 enzyme I and II, activity in Tris-buffer higher than in phosphate buffer Treponema denticola

pH Range

pH Minimum pH Maximum Comment Organism
5
-
no activity below Treponema denticola