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Literature summary for 3.4.11.4 extracted from
- Tripeptidyl-peptidase II controls DNA damage responses and in vivo gamma-irradiation resistance of tumors (2007), Cancer Res., 67, 7165-7174.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Ala-Ala-Phe-chloromethylketone | - |
Homo sapiens |  |
| Ala-Ala-Phe-chloromethylketone | - |
Mus musculus | |
| butabindide | - |
Homo sapiens | |
| butabindide | - |
Mus musculus | |
| Z-Gly-Leu-Ala-OH | - |
Homo sapiens | |
| Z-Gly-Leu-Ala-OH | - |
Mus musculus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Mus musculus | 5829 | - |
| cytosol | - |
Homo sapiens | 5829 | - |
| nucleus | subsequent relocalization into the nucleus following gamma-irradiation | Mus musculus | 5634 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| EL-4 cell | - |
Mus musculus | - |
| HeLa cell | - |
Homo sapiens | - |
| lymphoma cell | - |
Mus musculus | - |
| lymphoma cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Ala-Ala-Phe-7-amido-4-methylcoumarin + H2O | - |
Mus musculus | ? | - |
? | |
| Ala-Ala-Phe-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| TPPII | - |
Mus musculus |
| TPPII | - |
Homo sapiens |
| tripeptidyl-peptidase II | - |
Mus musculus |
| tripeptidyl-peptidase II | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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