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Literature summary for 3.4.11.4 extracted from

  • Lees, T.; Lauffart, B.; McDermott, J.; Gibson, A.; Mantle, D.
    Purification and characterization of tripeptidyl-aminopeptidase from human cerebral cortex (1990), Biochem. Soc. Trans., 18, 667.
    View publication on PubMed
Search for more literature for 3.4.11.4

Inhibitors

Inhibitors Comment Organism Structure
Cd2+
-
 Homo sapiens
Cu2+
-
 Homo sapiens
Hg2+
-
 Homo sapiens
N-ethylmaleimide
-
 Homo sapiens
p-Hydroxymercuriphenyl sulfonate
-
 Homo sapiens
Zn2+
-
 Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.25
-
 Ala-Ala-Phe-7-amido-4-methylcoumarin
-
 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
100000
-
 gel filtration Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
cerebral cortex
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Ala-Ala-Phe-4-methylcoumarin 7-amide + H2O
-
 Homo sapiens ?
-
 ?
angiotensin II + H2O
-
 Homo sapiens ?
-
 ?
cholecystokinin octapeptide + H2O
-
 Homo sapiens ?
-
 ?
enkephalin + H2O
-
 Homo sapiens ?
-
 ?
neurokinin alpha + H2O
-
 Homo sapiens ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.7
-
 in presence of 2 mM dithiothreitol Homo sapiens