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Literature summary for 3.4.11.3 extracted from

  • Axen, A.; Andersson, H.; Lindeberg, G.; Roennholm, H.; Kortesmaa, J.; Demaegdt, H.; Vauquelin, G.; Karlen, A.; Hallberg, M.
    Small potent ligands to the insulin-regulated aminopeptidase (IRAP)/AT(4) receptor (2007), J. Pept. Sci., 13, 434-444.
    View publication on PubMed
Search for more literature for 3.4.11.3

Inhibitors

Inhibitors Comment Organism Structure
L-Val-L-Tyr-L-Ile-2-aminomethylphenylacetic acid inhibits both IRAP and aminopeptidase N and induces proliferation of stem cells at low concentrations Homo sapiens
L-Val-L-Tyr-L-Ile-L-His-L-Pro-L-Phe i.e. angiotensin IV, adopts a gamma-turn in the C-terminal of its bioactive conformation Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0000019
-
 L-Val-L-Tyr-L-Ile-2-aminomethylphenylacetic acid pH 7.4, 37°C Homo sapiens
0.0000046
-
 L-Val-L-Tyr-L-Ile-L-His-L-Pro-L-Phe pH 7.4, 37°C Homo sapiens