Cloned (Comment) | Organism |
---|---|
expression in 3T3-L1 cell | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
L53A/L54A | no change in intracellular trafficking | Mus musculus |
L76A/L77A | mutation results in rapid default of the enzyme to the cell surface. In presence of a dominant interfering mutant of clathrin adaptor GGA1, insulin-stimulated translocation of wild-type enzyme, but not of mutant L76A/L77A is inhibited | Mus musculus |
additional information | alanine-substitution of 9 residues amino- or carboxy-terminal to the dileucine motif at positions 76, 77 does not perturb basal intracellular sequestration of the enzyme | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |