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Literature summary for 3.4.11.3 extracted from

  • Albiston, A.L.; Fernando, R.; Ye, S.; Peck, G.R.; Chai, S.Y.
    Alzheimer's, angiotensin IV and an aminopeptidase (2004), Biol. Pharm. Bull., 27, 765-767.
    View publication on PubMed

Application

Application Comment Organism
medicine development of stable second generation inhibitors of IRAP based on the AT4 ligands angiotensin IV or LVV-H7 may provide the opportunity for the development of therapeutics for memory loss in patients Altheimer's disease Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
angiotensin IV competitive Homo sapiens
LVV-H7 competitive Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasmic vesicle GLUT4-containing; the enzyme colocalizes with GLUT4 in specific intracellular vesicles Homo sapiens 31410
-
membrane type III integral membrane spanning protein Homo sapiens 16020
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Synonyms

Synonyms Comment Organism
insulin-regulated aminopeptidase
-
Homo sapiens
IRAP
-
Homo sapiens