Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | membrane-bound placental enzyme is released into maternal blood flow via proteolytic cleavage by metalloproteases and metalloproteinases | Homo sapiens | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
angiotensin III + H2O | Homo sapiens | the enzyme plays a role in blood pressure regulation via hydrolyzing vasopressin and angiotensin III | ? | - |
? | |
Vasopressin + H2O | Homo sapiens | the enzyme plays a role in blood pressure regulation via hydrolyzing vasopressin and angiotensin III | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood serum | during normal pregnancy, enzyme activity in maternal serum gradually increases to the maximum at near term | Homo sapiens | - |
placenta | the enzyme is predominantly expressed in differentiated trophoblasts | Homo sapiens | - |
trophoblast | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
angiotensin III + H2O | the enzyme plays a role in blood pressure regulation via hydrolyzing vasopressin and angiotensin III | Homo sapiens | ? | - |
? | |
Vasopressin + H2O | the enzyme plays a role in blood pressure regulation via hydrolyzing vasopressin and angiotensin III | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
P-LAP | - |
Homo sapiens |
Placental leucine aminopeptidase | - |
Homo sapiens |