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Literature summary for 3.4.11.3 extracted from

  • Mitsui, T.; Nomura, S.; Itakura, A.; Mizutani, S.
    Role of aminopeptidases in the blood pressure regulation (2004), Biol. Pharm. Bull., 27, 768-771.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane membrane-bound placental enzyme is released into maternal blood flow via proteolytic cleavage by metalloproteases and metalloproteinases Homo sapiens 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
angiotensin III + H2O Homo sapiens the enzyme plays a role in blood pressure regulation via hydrolyzing vasopressin and angiotensin III ?
-
?
Vasopressin + H2O Homo sapiens the enzyme plays a role in blood pressure regulation via hydrolyzing vasopressin and angiotensin III ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood serum during normal pregnancy, enzyme activity in maternal serum gradually increases to the maximum at near term Homo sapiens
-
placenta the enzyme is predominantly expressed in differentiated trophoblasts Homo sapiens
-
trophoblast
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
angiotensin III + H2O the enzyme plays a role in blood pressure regulation via hydrolyzing vasopressin and angiotensin III Homo sapiens ?
-
?
Vasopressin + H2O the enzyme plays a role in blood pressure regulation via hydrolyzing vasopressin and angiotensin III Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
P-LAP
-
Homo sapiens
Placental leucine aminopeptidase
-
Homo sapiens