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Literature summary for 3.4.11.3 extracted from
- Purification and properties of oxytocinase (cystine amino-peptidase) from monkey placenta (1976), J. Biochem., 80, 389-396.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Al3+ | - |
Macaca fuscata fuscata |  |
| Ca2+ | slightly | Macaca fuscata fuscata | |
| Cd2+ | - |
Macaca fuscata fuscata | |
| Co2+ | at high concentration inhibition | Macaca fuscata fuscata | |
| EDTA | - |
Macaca fuscata fuscata | |
| Hg2+ | - |
Macaca fuscata fuscata | |
| iodoacetic acid | slightly | Macaca fuscata fuscata | |
| Mn2+ | at high concentration inhibition; reverses EDTA inhibition | Macaca fuscata fuscata | |
| p-chloromercuribenzoate | - |
Macaca fuscata fuscata | |
| Zn2+ | - |
Macaca fuscata fuscata | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | - |
Macaca fuscata fuscata |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | reversal of EDTA inhibition | Macaca fuscata fuscata | |
| Co2+ | inhibition at high concentration | Macaca fuscata fuscata | |
| Mn2+ | reversal of EDTA inhibition, inhibition at high concentration | Macaca fuscata fuscata | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 87000 | - |
gel filtration | Macaca fuscata fuscata |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Macaca fuscata fuscata | - |
monkey | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Macaca fuscata fuscata |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| placenta | - |
Macaca fuscata fuscata | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.2087 | - |
- |
Macaca fuscata fuscata |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| oxytocin + H2O | - |
Macaca fuscata fuscata | acyclic peptide + H2O | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 87000, SDS-PAGE | Macaca fuscata fuscata |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.5 | - |
- |
Macaca fuscata fuscata |
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Release 2023.1 (January 2023)
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