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Literature summary for 3.4.11.3 extracted from

  • Sakura, H.; Lin, T.Y.; Doi, M.; Mizutani, S.; Kawashima, Y.
    Purification and properties of ocytocinase, a metalloenzyme (1981), Biochem. Int., 2, 173-179.
No PubMed abstract available
Search for more literature for 3.4.11.3

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline
-
 Homo sapiens
8-hydroxyquinoline
-
 Homo sapiens
Cd2+
-
 Homo sapiens
Cu2+
-
 Homo sapiens
EDTA
-
 Homo sapiens
EGTA
-
 Homo sapiens
Zn2+
-
 Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.029
-
 L-Trp-2-naphthylamide
-
 Homo sapiens
0.046
-
 L-Arg-2-naphthylamide
-
 Homo sapiens
0.5
-
 L-Ala-2-naphthylamide
-
 Homo sapiens
0.59
-
 L-Leu-2-naphthylamide
-
 Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ metalloenzyme Homo sapiens
Zn2+ 2 mol Zn2+ per subunit Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
140000
-
 2 * 140000, SDS-PAGE Homo sapiens
280000
-
 gel filtration Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
serum retroplacental Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.35
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Ala-2-naphthylamide + H2O
-
 Homo sapiens L-Ala + 2-naphthylamine
-
 ?
L-Arg-2-naphthylamide + H2O
-
 Homo sapiens L-Arg + 2-naphthylamine
-
 ?
L-Leu-2-naphthylamide + H2O
-
 Homo sapiens L-Leu + 2-naphthylamine
-
 ?
L-Lys-2-naphthylamide + H2O
-
 Homo sapiens L-Lys + 2-naphthylamine
-
 ?
L-Trp-2-naphthylamide + H2O
-
 Homo sapiens L-Trp + 2-naphthylamine
-
 ?
additional information not: L-Asp-beta-naphthylamide, L-Glu-beta-naphthylamide Homo sapiens ?
-
 ?
oxytocin + H2O cleavage of bond between N-terminal cysteine and adjacent tyrosine Homo sapiens acyclic peptide + H2O
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 140000, SDS-PAGE Homo sapiens