Cloned (Comment) | Organism |
---|---|
His-tagged truncated form expressed in Escherichia coli Rosetta2 BL21(DE3) | Plasmodium falciparum |
Crystallization (Comment) | Organism |
---|---|
hanging drop vapour diffusion method | Plasmodium falciparum |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
bestatin | - |
Plasmodium falciparum | |
EDTA | - |
Plasmodium falciparum | |
hPhe-PSI[PO2CH2]-Phe | phosphinic dipeptide analog | Plasmodium falciparum |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | - |
Plasmodium falciparum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Plasmodium falciparum | Q8IL11 | - |
- |
Purification (Comment) | Organism |
---|---|
immobilized metal ion affinity chromatography (Ni2+), gel filtration | Plasmodium falciparum |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Leu-7-amido-4-methyl-coumarin + H2O | - |
Plasmodium falciparum | L-leucine + 7-amino-4-methyl-coumarin | - |
? |
Subunits | Comment | Organism |
---|---|---|
homohexamer | crystal structure analysis | Plasmodium falciparum |
Synonyms | Comment | Organism |
---|---|---|
M17 leucyl aminopeptidase | - |
Plasmodium falciparum |
PfA-M17 | - |
Plasmodium falciparum |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000013 | - |
hPhe-PSI[PO2CH2]-Phe | pH and temperature not specified in the publication | Plasmodium falciparum | |
0.000025 | - |
bestatin | pH and temperature not specified in the publication | Plasmodium falciparum |