Literature summary for 3.4.11.2 extracted from

Grzywa, R.; Oleksyszyn, J.; Salvesen, G.S.; Drag, M.
Identification of very potent inhibitor of human aminopeptidase N (CD13) (2010), Bioorg. Med. Chem. Lett., 20, 2497-2499.

Inhibitors

Inhibitors	Comment	Organism
(1-amino-2-methylpropyl)(1-hydroxy-3-phenylpropyl)phosphinic acid	-	Homo sapiens
(1-amino-2-methylpropyl)(1-hydroxy-3-phenylpropyl)phosphinic acid	-	Rattus norvegicus
(1-amino-2-methylpropyl)(1-hydroxy-3-phenylpropyl)phosphinic acid	-	Sus scrofa
(1-amino-2-phenylethyl)(1-hydroxy-3-phenylpropyl)phosphinic acid	-	Homo sapiens
(1-amino-2-phenylethyl)(1-hydroxy-3-phenylpropyl)phosphinic acid	-	Rattus norvegicus
(1-amino-2-phenylethyl)(1-hydroxy-3-phenylpropyl)phosphinic acid	-	Sus scrofa
(1-amino-3-methylbutyl)(1-hydroxy-3-phenylpropyl)phosphinic acid	-	Homo sapiens
(1-amino-3-methylbutyl)(1-hydroxy-3-phenylpropyl)phosphinic acid	-	Rattus norvegicus
(1-amino-3-methylbutyl)(1-hydroxy-3-phenylpropyl)phosphinic acid	-	Sus scrofa
(1-aminobutyl)(1-hydroxy-2-phenylethyl)phosphinic acid	-	Homo sapiens
(1-aminobutyl)(1-hydroxy-2-phenylethyl)phosphinic acid	-	Rattus norvegicus
(1-aminobutyl)(1-hydroxy-2-phenylethyl)phosphinic acid	-	Sus scrofa
(1-aminoethyl)[hydroxy[4-(propan-2-yl)phenyl]methyl]phosphinic acid	-	Homo sapiens
(1-aminoethyl)[hydroxy[4-(propan-2-yl)phenyl]methyl]phosphinic acid	-	Rattus norvegicus
(1-aminoethyl)[hydroxy[4-(propan-2-yl)phenyl]methyl]phosphinic acid	-	Sus scrofa
(1-aminohexyl)((2-(methoxycarbonyl)benzyl)carbamothioyl)phosphinic acid	-	Homo sapiens
(1-aminohexyl)((2-(methoxycarbonyl)benzyl)carbamothioyl)phosphinic acid	-	Rattus norvegicus
(1-aminohexyl)((2-(methoxycarbonyl)benzyl)carbamothioyl)phosphinic acid	-	Sus scrofa
(1-aminopentyl)(1-hydroxy-2-phenylpropyl)phosphinic acid	-	Homo sapiens
(1-aminopentyl)(1-hydroxy-2-phenylpropyl)phosphinic acid	-	Rattus norvegicus
(1-aminopentyl)(1-hydroxy-2-phenylpropyl)phosphinic acid	-	Sus scrofa
(1-aminopentyl)(1-hydroxy-3-phenylpropyl)phosphinic acid	-	Homo sapiens
(1-aminopentyl)(1-hydroxy-3-phenylpropyl)phosphinic acid	-	Rattus norvegicus
(1-aminopentyl)(1-hydroxy-3-phenylpropyl)phosphinic acid	-	Sus scrofa
(1-aminopentyl)[hydroxy(4-hydroxyphenyl)methyl]phosphinic acid	-	Homo sapiens
(1-aminopentyl)[hydroxy(4-hydroxyphenyl)methyl]phosphinic acid	-	Rattus norvegicus
(1-aminopentyl)[hydroxy(4-hydroxyphenyl)methyl]phosphinic acid	-	Sus scrofa
(1-aminopropyl)(1-hydroxy-3-phenylpropyl)phosphinic acid	-	Homo sapiens
(1-aminopropyl)(1-hydroxy-3-phenylpropyl)phosphinic acid	-	Rattus norvegicus
(1-aminopropyl)(1-hydroxy-3-phenylpropyl)phosphinic acid	-	Sus scrofa
1-amino-2-methylpropyl(hexylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-amino-2-methylpropyl(hexylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-amino-2-methylpropyl(hexylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-amino-2-methylpropyl(isobutylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-amino-2-methylpropyl(isobutylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-amino-2-methylpropyl(isobutylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-amino-2-methylpropyl(methylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-amino-2-methylpropyl(methylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-amino-2-methylpropyl(methylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-amino-3-methylbutyl(2-(methoxycarbonyl)benzylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-amino-3-methylbutyl(2-(methoxycarbonyl)benzylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-amino-3-methylbutyl(2-(methoxycarbonyl)benzylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-amino-3-methylbutyl(benzylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-amino-3-methylbutyl(benzylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-amino-3-methylbutyl(benzylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-amino-3-methylbutyl(hexylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-amino-3-methylbutyl(hexylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-amino-3-methylbutyl(hexylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-amino-3-methylbutyl(methylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-amino-3-methylbutyl(methylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-amino-3-methylbutyl(methylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-amino-3-methylbutyl(phenethylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-amino-3-methylbutyl(phenethylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-amino-3-methylbutyl(phenethylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-amino-3-phenylpropyl(3-(methylthio)propylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-amino-3-phenylpropyl(3-(methylthio)propylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-amino-3-phenylpropyl(3-(methylthio)propylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-amino-3-phenylpropyl(4-(ethoxycarbonyl)benzylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-amino-3-phenylpropyl(4-(ethoxycarbonyl)benzylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-amino-3-phenylpropyl(4-(ethoxycarbonyl)benzylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-amino-3-phenylpropyl(4-methoxybenzylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-amino-3-phenylpropyl(4-methoxybenzylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-amino-3-phenylpropyl(4-methoxybenzylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-amino-3-phenylpropyl(benzylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-amino-3-phenylpropyl(benzylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-amino-3-phenylpropyl(benzylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-amino-3-phenylpropyl(propylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-amino-3-phenylpropyl(propylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-amino-3-phenylpropyl(propylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-aminobutyl(2-(methoxycarbonyl)phenethylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-aminobutyl(2-(methoxycarbonyl)phenethylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-aminobutyl(2-(methoxycarbonyl)phenethylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-aminobutyl(3-(methylthio)propylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-aminobutyl(3-(methylthio)propylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-aminobutyl(3-(methylthio)propylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-aminobutyl(4-(ethoxycarbonyl)phenethylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-aminobutyl(4-(ethoxycarbonyl)phenethylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-aminobutyl(4-(ethoxycarbonyl)phenethylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-aminobutyl(4-methoxyphenethylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-aminobutyl(4-methoxyphenethylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-aminobutyl(4-methoxyphenethylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-aminobutyl(benzylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-aminobutyl(benzylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-aminobutyl(benzylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-aminobutyl(phenethylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-aminobutyl(phenethylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-aminobutyl(phenethylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-aminoethyl(3-(methylthio)propylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-aminoethyl(3-(methylthio)propylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-aminoethyl(3-(methylthio)propylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-aminoethyl(4-(ethoxycarbonyl)benzylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-aminoethyl(4-(ethoxycarbonyl)benzylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-aminoethyl(4-(ethoxycarbonyl)benzylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-aminoethyl(4-methoxybenzylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-aminoethyl(4-methoxybenzylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-aminoethyl(4-methoxybenzylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-aminoethyl(benzylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-aminoethyl(benzylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-aminoethyl(benzylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-aminoethyl(phenethylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-aminoethyl(phenethylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-aminoethyl(phenethylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-aminopentyl(2-(methoxycarbonyl)benzylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-aminopentyl(2-(methoxycarbonyl)benzylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-aminopentyl(2-(methoxycarbonyl)benzylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-aminopentyl(3-(methylthio)propylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-aminopentyl(3-(methylthio)propylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-aminopentyl(3-(methylthio)propylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-aminopentyl(4-methoxybenzylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-aminopentyl(4-methoxybenzylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-aminopentyl(4-methoxybenzylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-aminopentyl(benzylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-aminopentyl(benzylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-aminopentyl(benzylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-aminopentyl(phenethylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-aminopentyl(phenethylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-aminopentyl(phenethylcarbamothioyl)phosphinic acid	-	Sus scrofa
1-aminopropyl(3-(methylthio)propylcarbamothioyl)phosphinic acid	-	Homo sapiens
1-aminopropyl(3-(methylthio)propylcarbamothioyl)phosphinic acid	-	Rattus norvegicus
1-aminopropyl(3-(methylthio)propylcarbamothioyl)phosphinic acid	-	Sus scrofa
4-(2-(((1-aminobutyl)(hydroxy)phosphoryl)methanethioamido)ethyl)benzoic acid	-	Homo sapiens
4-(2-(((1-aminobutyl)(hydroxy)phosphoryl)methanethioamido)ethyl)benzoic acid	-	Rattus norvegicus
4-(2-(((1-aminobutyl)(hydroxy)phosphoryl)methanethioamido)ethyl)benzoic acid	-	Sus scrofa
alpha1-amino-3-phenylpropyl(alpha2-hydroxy-3-phenylpropyl)phosphinic acid	very potent inhibitor of APN	Homo sapiens
alpha1-amino-3-phenylpropyl(alpha2-hydroxy-3-phenylpropyl)phosphinic acid	very potent inhibitor of APN	Rattus norvegicus
alpha1-amino-3-phenylpropyl(alpha2-hydroxy-3-phenylpropyl)phosphinic acid	very potent inhibitor of APN	Sus scrofa
[amino(phenyl)methyl](1-hydroxy-3-methylbutyl)phosphinic acid	-	Homo sapiens
[amino(phenyl)methyl](1-hydroxy-3-methylbutyl)phosphinic acid	-	Rattus norvegicus
[amino(phenyl)methyl](1-hydroxy-3-methylbutyl)phosphinic acid	-	Sus scrofa
[amino(phenyl)methyl](1-hydroxy-3-phenylpropyl)phosphinic acid	-	Homo sapiens
[amino(phenyl)methyl](1-hydroxy-3-phenylpropyl)phosphinic acid	-	Rattus norvegicus
[amino(phenyl)methyl](1-hydroxy-3-phenylpropyl)phosphinic acid	-	Sus scrofa
[amino(phenyl)methyl](1-hydroxyethyl)phosphinic acid	-	Homo sapiens
[amino(phenyl)methyl](1-hydroxyethyl)phosphinic acid	-	Rattus norvegicus
[amino(phenyl)methyl](1-hydroxyethyl)phosphinic acid	-	Sus scrofa
[amino(phenyl)methyl][hydroxy(phenyl)methyl]phosphinic acid	-	Homo sapiens
[amino(phenyl)methyl][hydroxy(phenyl)methyl]phosphinic acid	-	Rattus norvegicus
[amino(phenyl)methyl][hydroxy(phenyl)methyl]phosphinic acid	-	Sus scrofa

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-
Rattus norvegicus	-	-	-
Sus scrofa	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.
L-Ala-7-amido-4-methylcoumarin + H2O	-	Homo sapiens	L-Ala + 7-amino-4-methylcoumarin	-	?
L-Ala-7-amido-4-methylcoumarin + H2O	-	Rattus norvegicus	L-Ala + 7-amino-4-methylcoumarin	-	?
L-Ala-7-amido-4-methylcoumarin + H2O	-	Sus scrofa	L-Ala + 7-amino-4-methylcoumarin	-	?

Synonyms

Synonyms	Comment	Organism
aminopeptidase N	-	Homo sapiens
aminopeptidase N	-	Rattus norvegicus
aminopeptidase N	-	Sus scrofa
APN	-	Homo sapiens
APN	-	Rattus norvegicus
APN	-	Sus scrofa
CD13	-	Homo sapiens
CD13	-	Rattus norvegicus
CD13	-	Sus scrofa

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor
0.00006	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	alpha1-amino-3-phenylpropyl(alpha2-hydroxy-3-phenylpropyl)phosphinic acid
0.000145	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-aminoethyl(benzylcarbamothioyl)phosphinic acid
0.00021	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	(1-aminopentyl)(1-hydroxy-3-phenylpropyl)phosphinic acid
0.00022	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	(1-aminopentyl)(1-hydroxy-3-phenylpropyl)phosphinic acid
0.00022	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	(1-aminopentyl)(1-hydroxy-2-phenylpropyl)phosphinic acid
0.00022	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	alpha1-amino-3-phenylpropyl(alpha2-hydroxy-3-phenylpropyl)phosphinic acid
0.00024	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	[amino(phenyl)methyl](1-hydroxy-3-phenylpropyl)phosphinic acid
0.00025	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	(1-amino-2-methylpropyl)(1-hydroxy-3-phenylpropyl)phosphinic acid
0.00025	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-aminopentyl(phenethylcarbamothioyl)phosphinic acid
0.00036	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-aminopentyl(3-(methylthio)propylcarbamothioyl)phosphinic acid
0.0004	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	alpha1-amino-3-phenylpropyl(alpha2-hydroxy-3-phenylpropyl)phosphinic acid
0.00042	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	(1-amino-3-methylbutyl)(1-hydroxy-3-phenylpropyl)phosphinic acid
0.00046	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-aminopentyl(4-methoxybenzylcarbamothioyl)phosphinic acid
0.00046	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	[amino(phenyl)methyl][hydroxy(phenyl)methyl]phosphinic acid
0.00046	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	(1-aminopentyl)(1-hydroxy-2-phenylpropyl)phosphinic acid
0.00047	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-amino-3-phenylpropyl(3-(methylthio)propylcarbamothioyl)phosphinic acid
0.0005	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	(1-amino-2-methylpropyl)(1-hydroxy-3-phenylpropyl)phosphinic acid
0.00052	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	(1-aminopentyl)(1-hydroxy-3-phenylpropyl)phosphinic acid
0.00055	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	[amino(phenyl)methyl][hydroxy(phenyl)methyl]phosphinic acid
0.00056	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-amino-3-phenylpropyl(propylcarbamothioyl)phosphinic acid
0.0006	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	(1-aminopropyl)(1-hydroxy-3-phenylpropyl)phosphinic acid
0.00061	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-aminopentyl(3-(methylthio)propylcarbamothioyl)phosphinic acid
0.00062	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-aminopentyl(phenethylcarbamothioyl)phosphinic acid
0.00062	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-aminopentyl(benzylcarbamothioyl)phosphinic acid
0.00064	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-amino-3-phenylpropyl(4-methoxybenzylcarbamothioyl)phosphinic acid
0.00064	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-aminopentyl(4-methoxybenzylcarbamothioyl)phosphinic acid
0.00066	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	(1-amino-2-phenylethyl)(1-hydroxy-3-phenylpropyl)phosphinic acid
0.00071	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-aminopentyl(phenethylcarbamothioyl)phosphinic acid
0.00073	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	[amino(phenyl)methyl](1-hydroxy-3-phenylpropyl)phosphinic acid
0.00077	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-aminopentyl(3-(methylthio)propylcarbamothioyl)phosphinic acid
0.00086	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	(1-aminopentyl)(1-hydroxy-2-phenylpropyl)phosphinic acid
0.00087	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	(1-aminoethyl)[hydroxy[4-(propan-2-yl)phenyl]methyl]phosphinic acid
0.00092	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	(1-amino-3-methylbutyl)(1-hydroxy-3-phenylpropyl)phosphinic acid
0.00093	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	(1-amino-2-phenylethyl)(1-hydroxy-3-phenylpropyl)phosphinic acid
0.00095	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	(1-aminobutyl)(1-hydroxy-2-phenylethyl)phosphinic acid
0.00096	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-amino-3-methylbutyl(hexylcarbamothioyl)phosphinic acid
0.001	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	(1-amino-3-methylbutyl)(1-hydroxy-3-phenylpropyl)phosphinic acid
0.00105	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-aminopentyl(4-methoxybenzylcarbamothioyl)phosphinic acid
0.0011	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	(1-amino-2-methylpropyl)(1-hydroxy-3-phenylpropyl)phosphinic acid
0.0011	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-aminopentyl(benzylcarbamothioyl)phosphinic acid
0.0012	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-amino-2-methylpropyl(hexylcarbamothioyl)phosphinic acid
0.0012	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	(1-aminobutyl)(1-hydroxy-2-phenylethyl)phosphinic acid
0.0012	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	(1-aminoethyl)[hydroxy[4-(propan-2-yl)phenyl]methyl]phosphinic acid
0.00125	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-aminobutyl(benzylcarbamothioyl)phosphinic acid
0.0013	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	(1-aminopropyl)(1-hydroxy-3-phenylpropyl)phosphinic acid
0.0013	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-amino-3-phenylpropyl(benzylcarbamothioyl)phosphinic acid
0.00135	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-aminobutyl(phenethylcarbamothioyl)phosphinic acid
0.00135	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-amino-3-phenylpropyl(propylcarbamothioyl)phosphinic acid
0.0014	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-amino-3-methylbutyl(hexylcarbamothioyl)phosphinic acid
0.00145	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-aminobutyl(3-(methylthio)propylcarbamothioyl)phosphinic acid
0.00145	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-aminobutyl(3-(methylthio)propylcarbamothioyl)phosphinic acid
0.00145	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-amino-3-phenylpropyl(propylcarbamothioyl)phosphinic acid
0.0015	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	[amino(phenyl)methyl][hydroxy(phenyl)methyl]phosphinic acid
0.0015	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-aminopentyl(benzylcarbamothioyl)phosphinic acid
0.00155	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-amino-3-phenylpropyl(3-(methylthio)propylcarbamothioyl)phosphinic acid
0.0016	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	(1-amino-2-phenylethyl)(1-hydroxy-3-phenylpropyl)phosphinic acid
0.0016	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-aminobutyl(benzylcarbamothioyl)phosphinic acid
0.0016	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-aminopropyl(3-(methylthio)propylcarbamothioyl)phosphinic acid
0.00165	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-aminopropyl(3-(methylthio)propylcarbamothioyl)phosphinic acid
0.00165	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-amino-3-phenylpropyl(3-(methylthio)propylcarbamothioyl)phosphinic acid
0.0017	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-amino-2-methylpropyl(hexylcarbamothioyl)phosphinic acid
0.0017	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-amino-3-methylbutyl(hexylcarbamothioyl)phosphinic acid
0.0019	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-aminoethyl(benzylcarbamothioyl)phosphinic acid
0.00195	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-aminobutyl(3-(methylthio)propylcarbamothioyl)phosphinic acid
0.002	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	(1-aminobutyl)(1-hydroxy-2-phenylethyl)phosphinic acid
0.0021	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-aminobutyl(benzylcarbamothioyl)phosphinic acid
0.00215	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-aminobutyl(4-methoxyphenethylcarbamothioyl)phosphinic acid
0.00215	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-aminobutyl(4-methoxyphenethylcarbamothioyl)phosphinic acid
0.0022	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	[amino(phenyl)methyl](1-hydroxy-3-phenylpropyl)phosphinic acid
0.0022	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-aminoethyl(benzylcarbamothioyl)phosphinic acid
0.0023	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-amino-3-phenylpropyl(benzylcarbamothioyl)phosphinic acid
0.0024	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	(1-aminopropyl)(1-hydroxy-3-phenylpropyl)phosphinic acid
0.00245	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-aminobutyl(4-methoxyphenethylcarbamothioyl)phosphinic acid
0.00245	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-aminoethyl(3-(methylthio)propylcarbamothioyl)phosphinic acid
0.0025	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-aminopropyl(3-(methylthio)propylcarbamothioyl)phosphinic acid
0.0025	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-amino-3-phenylpropyl(benzylcarbamothioyl)phosphinic acid
0.00252	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-aminoethyl(3-(methylthio)propylcarbamothioyl)phosphinic acid
0.00255	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-aminobutyl(phenethylcarbamothioyl)phosphinic acid
0.00265	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-amino-3-phenylpropyl(4-methoxybenzylcarbamothioyl)phosphinic acid
0.00265	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-amino-3-phenylpropyl(4-methoxybenzylcarbamothioyl)phosphinic acid
0.0028	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-amino-3-methylbutyl(benzylcarbamothioyl)phosphinic acid
0.00345	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-aminoethyl(3-(methylthio)propylcarbamothioyl)phosphinic acid
0.0035	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	(1-aminoethyl)[hydroxy[4-(propan-2-yl)phenyl]methyl]phosphinic acid
0.0036	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-aminobutyl(phenethylcarbamothioyl)phosphinic acid
0.0042	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-amino-3-methylbutyl(phenethylcarbamothioyl)phosphinic acid
0.0044	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	[amino(phenyl)methyl](1-hydroxy-3-methylbutyl)phosphinic acid
0.0047	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	[amino(phenyl)methyl](1-hydroxy-3-methylbutyl)phosphinic acid
0.0048	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-amino-2-methylpropyl(isobutylcarbamothioyl)phosphinic acid
0.00505	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-amino-2-methylpropyl(hexylcarbamothioyl)phosphinic acid
0.0051	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-amino-3-methylbutyl(benzylcarbamothioyl)phosphinic acid
0.0052	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-aminoethyl(phenethylcarbamothioyl)phosphinic acid
0.0054	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-amino-3-methylbutyl(phenethylcarbamothioyl)phosphinic acid
0.0058	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-aminoethyl(phenethylcarbamothioyl)phosphinic acid
0.0058	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	(1-aminopentyl)[hydroxy(4-hydroxyphenyl)methyl]phosphinic acid
0.0062	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	(1-aminopentyl)[hydroxy(4-hydroxyphenyl)methyl]phosphinic acid
0.0082	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-amino-3-methylbutyl(benzylcarbamothioyl)phosphinic acid
0.0087	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-aminoethyl(phenethylcarbamothioyl)phosphinic acid
0.00895	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-amino-2-methylpropyl(isobutylcarbamothioyl)phosphinic acid
0.0093	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	(1-aminopentyl)[hydroxy(4-hydroxyphenyl)methyl]phosphinic acid
0.01015	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-amino-2-methylpropyl(methylcarbamothioyl)phosphinic acid
0.0108	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-amino-3-methylbutyl(methylcarbamothioyl)phosphinic acid
0.0114	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-amino-3-phenylpropyl(4-(ethoxycarbonyl)benzylcarbamothioyl)phosphinic acid
0.012	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	[amino(phenyl)methyl](1-hydroxy-3-methylbutyl)phosphinic acid
0.0146	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-amino-2-methylpropyl(methylcarbamothioyl)phosphinic acid
0.0152	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	[amino(phenyl)methyl](1-hydroxyethyl)phosphinic acid
0.01535	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-amino-2-methylpropyl(isobutylcarbamothioyl)phosphinic acid
0.0182	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	[amino(phenyl)methyl](1-hydroxyethyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-amino-3-methylbutyl(methylcarbamothioyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-amino-3-methylbutyl(methylcarbamothioyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-aminoethyl(4-methoxybenzylcarbamothioyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-aminoethyl(4-methoxybenzylcarbamothioyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-aminoethyl(4-methoxybenzylcarbamothioyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	4-(2-(((1-aminobutyl)(hydroxy)phosphoryl)methanethioamido)ethyl)benzoic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	4-(2-(((1-aminobutyl)(hydroxy)phosphoryl)methanethioamido)ethyl)benzoic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	4-(2-(((1-aminobutyl)(hydroxy)phosphoryl)methanethioamido)ethyl)benzoic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	(1-aminohexyl)((2-(methoxycarbonyl)benzyl)carbamothioyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	(1-aminohexyl)((2-(methoxycarbonyl)benzyl)carbamothioyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	(1-aminohexyl)((2-(methoxycarbonyl)benzyl)carbamothioyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-aminobutyl(2-(methoxycarbonyl)phenethylcarbamothioyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-aminobutyl(2-(methoxycarbonyl)phenethylcarbamothioyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-aminobutyl(2-(methoxycarbonyl)phenethylcarbamothioyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-amino-3-phenylpropyl(4-(ethoxycarbonyl)benzylcarbamothioyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-amino-3-phenylpropyl(4-(ethoxycarbonyl)benzylcarbamothioyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-aminoethyl(4-(ethoxycarbonyl)benzylcarbamothioyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-aminoethyl(4-(ethoxycarbonyl)benzylcarbamothioyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-aminoethyl(4-(ethoxycarbonyl)benzylcarbamothioyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-aminopentyl(2-(methoxycarbonyl)benzylcarbamothioyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-aminopentyl(2-(methoxycarbonyl)benzylcarbamothioyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-aminopentyl(2-(methoxycarbonyl)benzylcarbamothioyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-aminobutyl(4-(ethoxycarbonyl)phenethylcarbamothioyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-aminobutyl(4-(ethoxycarbonyl)phenethylcarbamothioyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-aminobutyl(4-(ethoxycarbonyl)phenethylcarbamothioyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-amino-3-methylbutyl(2-(methoxycarbonyl)benzylcarbamothioyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-amino-3-methylbutyl(2-(methoxycarbonyl)benzylcarbamothioyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	1-amino-3-methylbutyl(2-(methoxycarbonyl)benzylcarbamothioyl)phosphinic acid
0.02	-	IC50 above 0.02 mM, at 37°C in 100 mM Tris-HCl, pH 7.5	Homo sapiens	1-amino-3-methylbutyl(phenethylcarbamothioyl)phosphinic acid
0.02135	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Rattus norvegicus	1-amino-2-methylpropyl(methylcarbamothioyl)phosphinic acid
0.048	-	at 37°C in 100 mM Tris-HCl, pH 7.5	Sus scrofa	[amino(phenyl)methyl](1-hydroxyethyl)phosphinic acid