Application | Comment | Organism |
---|---|---|
medicine | aminopeptidase N-null mice develop normally without physiological alterations and can undergo physiological angiogenesis but show a severely impaired angiogenic response under pathological conditions | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | mice with targeted disruption of the aminopeptidase N gene develop with no gross or histological abnormalities. In oxygen-induced retinopathy experiments, enzyme deficient mice have a marked and dose-dependent deficiency of the expected retinal neovascularization | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |