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Literature summary for 3.4.11.2 extracted from

  • Sonneck, K.; Baumgartner, C.; Rebuzzi, L.; Marth, K.; Chen, K.W.; Hauswirth, A.W.; Florian, S.; Vrtala, S.; Buehring, H.J.; Valenta, R.; Valent, P.
    Recombinant allergens promote expression of aminopeptidase-N (CD13) on basophils in allergic patients (2008), Int. J. Immunopathol. Pharmacol., 21, 11-21.
    View publication on PubMed

Application

Application Comment Organism
medicine exposure of blood basophils from patients allergic to grass pollen, birch pollen, or house dust mites to their respective allergen results in up-regulation of CD13 in all sensitized individual, whereas in healthy controls no increase is seen. Increase in CD13 requires extracellular calcium and is counteracted by preincubation of cells with staurosporin or LY294002 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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isoform CD13, patients allergic to grass pollen, birch pollen, or house dust mites
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Source Tissue

Source Tissue Comment Organism Textmining
basophil
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Homo sapiens
-