Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.11.2 extracted from

  • Terauchi, M.; Kajiyama, H.; Shibata, K.; Ino, K.; Nawa, A.; Mizutani, S.; Kikkawa, F.
    Inhibition of APN/CD13 leads to suppressed progressive potential in ovarian carcinoma cells (2007), BMC Cancer, 7, 140.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine daily intraperitoneal administration of bestatin after inoculation of ovarian cancer cells results in a decrease of peritoneal dissemination and in prologed survival of animals Mus musculus
medicine positive correlation between CD13 expression and migratory potential in various ovarian cancer cell lines, and significant decrease in the proliferative and migratory abilities of cell lines after the addition of enzyme inhibitor bestatin or its inhibiton by siRNA Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
isoform CD13
-
Mus musculus
-
isoform CD13
-

Source Tissue

Source Tissue Comment Organism Textmining
ovary cancer cell
-
Mus musculus
-
ovary cancer cell
-
Homo sapiens
-