Any feedback?
Literature summary for 3.4.11.2 extracted from
- CD13/aminopeptidase N and murine cytomegalovirus infection (2005), Virology, 334, 1-9.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,10-phenanthroline | - |
Homo sapiens |  |
| 1,10-phenanthroline | - |
Mus musculus | |
| EDTA | - |
Homo sapiens | |
| EDTA | - |
Mus musculus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| brush border | - |
Mus musculus | 5903 | - |
| brush border | - |
Homo sapiens | 5903 | - |
| cell surface | - |
Mus musculus | 9986 | - |
| cell surface | - |
Homo sapiens | 9986 | - |
| membrane | bound, brush border | Mus musculus | 16020 | - |
| membrane | bound, brush border | Homo sapiens | 16020 | - |
| plasma membrane | - |
Mus musculus | 5886 | - |
| plasma membrane | - |
Homo sapiens | 5886 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| additional information | metallopeptidase | Mus musculus | |
| additional information | metallopeptidase | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | the enzyme is involved in infection of cells with human cytomegalovirus and in pathogenesis, enzyme inhibition reduces the infection rate, infection induces the production of anti-CD13 antibodies, overview | ? | - |
? | |
| additional information | Mus musculus | the enzyme is involved in infection of cells with murine cytomegalovirus and in pathogenesis, enzyme inhibition reduces the infection rate, infection induces the production of anti-CD13 antibodies, overview | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| 3T12 cell | fibroblast cell line | Mus musculus | - |
| bone marrow | - |
Mus musculus | - |
| bone marrow | - |
Homo sapiens | - |
| endothelial cell | - |
Mus musculus | - |
| endothelial cell | - |
Homo sapiens | - |
| fibroblast | - |
Mus musculus | - |
| fibroblast | - |
Homo sapiens | - |
| MEF cell | fibroblast cell line | Mus musculus | - |
| NIH-3T3 cell | fibroblast cell line | Mus musculus | - |
| Py-41 cell | endothelial cell line | Mus musculus | - |
| salivary gland | - |
Mus musculus | - |
| SVEC-4 cell | endothelial cell line | Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-Ala-4-nitroanilide + H2O | - |
Mus musculus | L-Ala + 4-nitroaniline | - |
? | |
| L-Ala-4-nitroanilide + H2O | - |
Homo sapiens | L-Ala + 4-nitroaniline | - |
? | |
| additional information | the enzyme is involved in infection of cells with human cytomegalovirus and in pathogenesis, enzyme inhibition reduces the infection rate, infection induces the production of anti-CD13 antibodies, overview | Homo sapiens | ? | - |
? | |
| additional information | the enzyme is involved in infection of cells with murine cytomegalovirus and in pathogenesis, enzyme inhibition reduces the infection rate, infection induces the production of anti-CD13 antibodies, overview | Mus musculus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| aminopeptidase N | - |
Mus musculus |
| aminopeptidase N | - |
Homo sapiens |
| CD13 | - |
Mus musculus |
| CD13 | - |
Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
