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Literature summary for 3.4.11.2 extracted from

  • Lee, J.; Shim, J.S.; Jung, S.A.; Lee, S.T.; Kwon, H.J.
    N-hydroxy-2-(naphthalene-2-ylsulfanyl)-acetamide, a novel hydroxamic acid-based inhibitor of aminopeptidase N and its anti-angiogenic activity (2005), Bioorg. Med. Chem. Lett., 15, 181-183.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
N-hydroxy-2-(naphthalene-2-ylsulfanyl)-acetamide inhibitor with a metal-chelating hydroxamate group, potent inhibition, anti-angiogenic activity and inhibition of basic fibroblast growth factor-induced invasion of aortic endothelial cells Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
aorta endothelial cell Bos taurus
-
endothelial cell aortic Bos taurus
-

Synonyms

Synonyms Comment Organism
aminopeptidase N
-
Bos taurus
APN
-
Bos taurus

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0035
-
N-hydroxy-2-(naphthalene-2-ylsulfanyl)-acetamide
-
Bos taurus