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Literature summary for 3.4.11.18 extracted from

  • Tucker, L.A.; Zhang, Q.; Sheppard, G.S.; Lou, P.; Jiang, F.; McKeegan, E.; Lesniewski, R.; Davidsen, S.K.; Bell, R.L.; Wang, J.
    Ectopic expression of methionine aminopeptidase-2 causes cell transformation and stimulates proliferation (2008), Oncogene, 2008, 1-10.
    View publication on PubMed
Search for more literature for 3.4.11.18

Cloned(Commentary)

Cloned (Comment) Organism
expressed in NIH-3T3 cells and NL20 cell line Homo sapiens

Protein Variants

Protein Variants Comment Organism
H231N enzymatically inactive Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
A-357300
-
 Homo sapiens
A-800141
-
 Homo sapiens
fumagillin
-
 Homo sapiens
TNP-470 irreversible inhibitor Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P50579
-
-

Source Tissue

Source Tissue Comment Organism Textmining
breast carcinoma cell
-
 Homo sapiens
-
Calu-6 cell
-
 Homo sapiens
-
colonic cancer cell
-
 Homo sapiens
-
DLD-1 cell
-
 Homo sapiens
-
HCT-116 cell
-
 Homo sapiens
-
HCT-15 cell
-
 Homo sapiens
-
HT-1080 cell
-
 Homo sapiens
-
LoVo cell
-
 Homo sapiens
-
lung adenocarcinoma cell
-
 Homo sapiens
-
NCI-H1299 cell
-
 Homo sapiens
-
NCI-H460 cell
-
 Homo sapiens
-
ovary cancer cell
-
 Homo sapiens
-
PC-3 cell
-
 Homo sapiens
-
prostate cancer cell
-
 Homo sapiens
-
SW-620 cell
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
MetAP2
-
 Homo sapiens
methionine aminopeptidase-2
-
 Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.000003
-
-
 Homo sapiens TNP-470
0.00002
-
-
 Homo sapiens A-800141
0.00015
-
-
 Homo sapiens A-357300