Literature summary for 3.4.11.18 extracted from

Ma, Z.Q.; Xie, S.X.; Huang, Q.Q.; Nan, F.J.; Hurley, T.D.; Ye, Q.Z.
Structural analysis of inhibition of E. coli methionine aminopeptidase: implication of loop adaptability in selective inhibition of bacterial enzymes (2007), BMC Struct. Biol., 7, 84.

Search for more literature for 3.4.11.18

Crystallization (Commentary)

Crystallization (Comment)	Organism
hanging drop vapour diffusion method, in complex with inhibitors, with 10-15% PEG 20000, 0.1 M MES (pH 6.5) and 0.2 mM MnCl2	Escherichia coli

Inhibitors

Inhibitors	Comment	Organism	Structure
5-(2,5-dichlorophenyl)furan-2-carboxylic acid	-	Escherichia coli
5-(2-chloro-4-nitrophenyl)furan-2-carboxylic acid	-	Escherichia coli
5-(2-chlorobenzyl)furan-2-carboxylic acid	-	Escherichia coli
5-(2-chlorophenyl)furan-2-carboxylic acid	-	Escherichia coli
5-(2-methoxyphenyl)furan-2-carboxylic acid	-	Escherichia coli
5-(2-nitrophenyl)furan-2-carboxylic acid	-	Escherichia coli
5-[2-(trifluoromethoxy)phenyl]furan-2-carboxylic acid	-	Escherichia coli
5-[2-(trifluoromethyl)phenyl]furan-2-carboxylic acid	-	Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
Met-peptide + H2O	Escherichia coli	-	Met + peptide	-	?

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	P0AE18	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Escherichia coli

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Met-peptide + H2O	-	Escherichia coli	Met + peptide	-	?

Synonyms

Synonyms	Comment	Organism
MetAP	-	Escherichia coli
methionine aminopeptidase	-	Escherichia coli

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)