Application | Comment | Organism |
---|---|---|
medicine | enzyme inhibitor PPI-2458 inhibits proliferation of human fibroblast-like synviocytes derived from patients with rheumatoid arthritis with a growth inhibitory concentration of 0.04 nM. Growth inhibition is linked to enzyme inhibition | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
PPI-2458 | irreversible | Homo sapiens | |
TNP-470 | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
patients with rheumatoid arthritis | - |