Application | Comment | Organism |
---|---|---|
medicine | enzyme expression is increased in 8 out of 12 tumor samples. Reduction of enzyme level by MAP1D shRNa does not result in any difference of proliferation, cell survival, or cell numbers, but cells exhibit a dramatically reduced potential to form colonies in soft agar | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
expressed in Sf21 insect cells | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
50000 | - |
SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Homo sapiens | - |
colon cancer cell lines and patiens with colon tumors | - |
Purification (Comment) | Organism |
---|---|
glutathione agarose chromatography | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
carcinoma cell | overexpression in colon cancer cell | Homo sapiens | - |
colon | overexpression in colon cancer cell | Homo sapiens | - |
colonic cancer cell | - |
Homo sapiens | - |
HCT-116 cell | - |
Homo sapiens | - |
HCT-116 cell | and HT-29 cell, highest expression levels found | Homo sapiens | - |
HT-29 cell | and HCT-116 cell, highest expression levels found | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Met-Ala-Ser + H2O | - |
Homo sapiens | Met + Ala-Ser | - |
? | |
additional information | no activity when using Glu-Ala-Ser and Leu-Ala-Ser peptides as substrates | Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 50000, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
MAP1D | - |
Homo sapiens |
methionine aminopeptidase | - |
Homo sapiens |