Crystallization (Comment) | Organism |
---|---|
Mn(II)-form of enzyme, in complex with inhibitor 5-(2-chlorophenyl)-2-furoic acid | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5-(2-(trifluoromethyl)phenyl)-2-furoic acid | Co(II)-form of enzyme, 50% inhibition at 0.073 mM, Mn(II)-form, 50% inhibition at 0.000063 mM, Ni-(II)form, 50% inhibition above 200 mM, Fe-(II)form, 50% inhibition at 0.195 mM | Escherichia coli | |
5-(2-chloro-3-methylphenyl)-2-furoic acid | Co(II)-form of enzyme, 50% inhibition at 0.069 mM, Mn(II)-form, 50% inhibition at 0.00096 mM, Ni-(II)form, 50% inhibition above 200 mM, Fe-(II)form, 50% inhibition above 200 mM | Escherichia coli | |
5-(2-chlorophenyl)-2-furoic acid | Co(II)-form of enzyme, 50% inhibition at 0.154 mM, Mn(II)-form, 50% inhibition at 0.0024 mM, Ni-(II)form, 50% inhibition above 200 mM, Fe-(II)form, 50% inhibition at 0.186 mM | Escherichia coli | |
5-(2-fluorophenyl)-2-furoic acid | Co(II)-form of enzyme, 50% inhibition at 0.198 mM, Mn(II)-form, 50% inhibition at 0.014 mM, Ni-(II)form, 50% inhibition above 200 mM, Fe-(II)form, 50% inhibition above 200 mM | Escherichia coli | |
5-(3-chlorophenyl)-2-furoic acid | Co(II)-form of enzyme, 50% inhibition at 0.193 mM, Mn(II)-form, 50% inhibition at 0.019 mM, Ni-(II)form, 50% inhibition above 200 mM, Fe-(II)form, 50% inhibition above 200 mM | Escherichia coli | |
N-(pyridin-2-ylmethyl)-N'-1,3-thiazol-2-ylethanediamide | Co(II)-form of enzyme, 50% inhibition at 0.000073 mM, Mn(II)-form, 50% inhibition at 0.043 mM, Ni-(II)form, 50% inhibition at 0.002 mM, Fe-(II)form, 50% inhibition at 0.065 mM | Escherichia coli | |
N-cyclopentyl-N'-1,3-thiazol-2-ylethanediamide | Co(II)-form of enzyme, 50% inhibition at 0.000067 mM, Mn(II)-form, 50% inhibition at 0.053 mM, Ni-(II)form, 50% inhibition at 0.001 mM, Fe-(II)form, 50% inhibition at 0.046 mM | Escherichia coli | |
N-isobutyl-N'-1,3-thiazol-2-ylethanediamide | Co(II)-form of enzyme, 50% inhibition at 0.00028 mM, Mn(II)-form, 50% inhibition at 0.108 mM, Ni-(II)form, 50% inhibition at 0.0034 mM, Fe-(II)form, 50% inhibition at 0.118 mM | Escherichia coli |
Organism | UniProt | Comment | Textmining |
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Escherichia coli | - |
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- |