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Literature summary for 3.4.11.18 extracted from

  • Son, K.H.; Kwon, J.Y.; Jeong, H.W.; Kim, H.K.; Kim, C.J.; Chang, Y.H.; Choi, J.D.; Kwon, B.M.
    5-demethylovalicin, as a methionine aminopeptidase-2 inhibitor produced by Chrysosporium (2002), Bioorg. Med. Chem., 10, 185-188.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
5-demethylovalicin IC50: 17.7 nM, inhibition of recombinant enzyme Homo sapiens
ovalicin
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Met-Gly-Met-Met + H2O
-
Homo sapiens Met + Gly-Met-Met
-
?

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0000177
-
IC50: 17.7 nM, inhibition of recombinant enzyme Homo sapiens 5-demethylovalicin