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Literature summary for 3.4.11.1 extracted from

  • Xu, Y.Z.; Shawar, S.M.; Dresden, M.H.
    Schistosoma mansoni: Purification and characterization of a membrane-associated leucine aminopeptidase (1990), Exp. Parasitol., 70, 124-133.
    View publication on PubMed
Search for more literature for 3.4.11.1

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline
-
 Schistosoma mansoni
2,2'-dipyridyl
-
 Schistosoma mansoni
2-mercaptoethylamine
-
 Schistosoma mansoni
amastatin
-
 Schistosoma mansoni
bestatin
-
 Schistosoma mansoni
leucine hydroxymate
-
 Schistosoma mansoni

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
35.8
-
 Leu-7-amino-4-trilfluoromethylcoumarin
-
 Schistosoma mansoni

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Schistosoma mansoni 16020
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
14000
-
 2 * 14000, SDS-PAGE Schistosoma mansoni
326000 360000 gel filtration Schistosoma mansoni

Organism

Organism UniProt Comment Textmining
Schistosoma mansoni
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Schistosoma mansoni

Source Tissue

Source Tissue Comment Organism Textmining
egg
-
 Schistosoma mansoni
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
16.52
-
-
 Schistosoma mansoni

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Leu-4-trifluoroomethylcoumarin-7-amide + H2O
-
 Schistosoma mansoni Leu + 7-amino-4-trifluoromethylcoumarin
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 14000, SDS-PAGE Schistosoma mansoni

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
-
 Schistosoma mansoni

pH Range

pH Minimum pH Maximum Comment Organism
5.8 8.1
-
 Schistosoma mansoni